Russ Swan, Editor, writes:
We see from your search that you're looking for information on the term "Single Nucleotide",
and we have a large number of manufacturers' news releases and technical articles here on Laboratorytalk which will be of interest.
Let me be your guide.
Start with
the news release Agreements with Geospiza and GenomeQuest from
Applied Biosystems, which we summarised at the time by saying "Applied Biosystems's software development community has established two formal agreements intended to help scientists address next-generation sequencing bioinformatics challenges".
The day before,
we featured the news release First African human genome has been sequenced from
Illumina: "Sequencing of this HapMap sample was conducted internally and marks the first human genome sequence generated exclusively with paired reads of 35 to 50 bases in length".
In January 2008, we covered the news from Illumina
concerning its Infinium HD Human610-Quad BeadChip
- take a look at BeadChips used in 10,000 sample Generation R study
which says: "Erasmus Medical Center in Rotterdam has purchased Illumina's Infinium HD (high-density) Human610-Quad BeadChips for the analysis of 10,000 samples and a third scanner to support the Generation R Study".
Take a look also at the news release from Illumina, Up to 2.3 million SNPs on a single chip,
as well as Sequencing the genome of the Pinot Noir grape from Roche Applied Science,
and Genetic markers can trace meat from farm to fork from Applied Biosystems.
See also:
Simplify workflows and expand use of TaqMan assays
(November 2007)
Applied Biosystems has signed a licensing and collaboration agreement with BioTrove to commercialise an analysis platform for high throughput genotyping applications
Solid to set new standards for genetic analysis
(October 2007)
Applied Biosystems says it has entered a new era of life-science research with the launch of its next-generation DNA sequencing platform, called Solid
Commentary on genetic variation in human genome
(October 2007)
This month in PLoS Biology (vol 5, issue 10), researchers published results from the sequencing of the first human diploid genome; all the DNA from both sets of chromosomes
Structural variation plays role in genetics
(September 2007)
454 Life Sciences, with Yale University researchers, has developed a method using the Genome Sequencer system to identify significant human genetic variability with an unprecedented level of detail
Funding doubles in cancer research
(September 2007)
Cancer Research UK funded a record £315m of research last year, marking a near doubling in research funding since the charity was formed five years ago
Genotyping service provider programme is launched
(August 2007)
Applied Biosystems has established a global genotyping service provider programme for scientists interested in the study of how specific genetic variations may impact health or disease
Early access to next-generation sequencing
(June 2007)
Applied Biosystems has shipped initial units of its Solid system to leading research institutions that include Stanford University, and has begun accepting orders from other customers
TaqMan gives improved data from real-time PCR
(April 2007)
For quantitative real-time PCR applications, the TaqMan Gene Expression Master Mix results in highly sensitive assays capable of detecting even a single copy of target nucleic acid in samples
Discovery of gene associated with Crohn's Disease
(January 2007)
Applied Biosystems genotyping technologies uncover new support for role of abnormal immune response to intestinal bacteria in the disease
Real-time PCR for low throughput applications
(January 2007)
Applied Biosystems announces a new instrument system for conducting genetic and genomic analysis experiments using real-time PCR (polymerase chain reaction) technology
ABsolute Blue master mix makes QPCR easier
(November 2006)
Inert blue dye, which does not effect the QPCR reaction, significantly enhances the contrast between reagent and plastic, making verification of master mix dispensing quick, easy and foolproof
Brothers in Arms win licence extension
(January 2006)
Amplification refractory mutation system technology (Arms) is a well-established and reliable method for the detection of genetic variations and single nucleotide polymorphisms (SNPs)
Speeding up high throughput scrapie genotyping
(November 2005)
Scrapie genotyping is based on a SNE assay that identifies four polymorphisms within the PRNP prion protein encoding gene affecting the susceptibility of an individual animal for the disease
DNA test for response to schizophrenia treatment
(November 2005)
New agreement brings personalised medicine services to psychiatry: first DNA test to predict individual patient response to clozapine
Molecular biology on second-generation chip system
(October 2005)
Open and robust platform allows laboratories to use one system for multiple molecular applications, including the detection of SNPs and multi-gene targets for pharmacogenetics
Five-year plan for cancer genotyping
(September 2005)
Agreement covers high-throughput genetics analysis using Grid computing platform for rapid development and publication of applications for cancer research
SNP market continues to grow
(August 2005)
48% of researchers expect the number of single nucleotide polymorphism (SNP) genotyping experiments they perform to increase in the next 12 months, according to this survey
Arms race leads to personalised medicine
(June 2005)
Amplification Refractory Mutation System technology is described as a well-established and reliable method for the detection of genetic variations and single nucleotide polymorphisms (SNPs)
European advances in genomics and proteomics
(April 2005)
Current research activities aim at going beyond the realm of human genome sequencing to expand the list of identified proteins and genes
Proteomics array confers full functionality
(February 2005)
Protein microarray has solved the long-standing dilemma of reduced protein functionality and erroneous protein conformation prevalent in many protein array methodologies
DNA workstation for forensics investigation
(November 2004)
Allows agencies to expedite processing of DNA analysis, which is becoming increasingly important in criminal investigations, and deal with backlog of untested samples
Very fast, very cheap genotyping
(April 2004)
System of reagents and software allows researchers to conduct ultra high throughput genotyping on the latest generation of capillary electrophoresis sequencing systems at a very low cost
DNA extraction for forensic samples
(March 2004)
Kit has been validated on follicles, cigarette butts and dried blood spots and can extract genomic DNA from sperm heads, epithelial cells, saliva, chewing gum and envelopes
Study of molecular mechanisms in tumour growth
(January 2004)
European Molecular Biology Laboratory uses bioarray system to better understand the underlying molecular changes in the transformation of pituitary tumours
Expanding SNP for paternity and forensic tests
(January 2004)
Collaboration agreement to develop and validate a genetic marker panel builds on success of of platform in scrapie susceptibility testing
DNA microarray patent licence expanded
(October 2003)
The expanded rights give Amersham access to OGT's sequence variation patents as well as core patents relating to analysing polynucleotide sequences
Comprehensive human bioarray
(September 2003)
Most comprehensive coverage of the P450 drug metabolising genes offered to date in this new bioarray, designed for screening clinical trial populations
Online discovery platform upgraded
(June 2003)
Latest enhancements will allow researchers to use comparative genomics in their discovery process more easily than before
Bioinformatics software agreement for Canada
(March 2003)
Distributor appointed for multi-platform sequence analysis software package and laboratory information management system
Sensitive SNP genotyping system
(December 2002)
Fast, simple and reliable method for genotyping single nucleotide polymorphisms can successfully genotype using reactions containing only 400pg of genomic DNA
Better genotype analysis
(October 2002)
Single nucleotide polymorphism (SNP) scoring functionality helps researchers analyse data quality and accuracy
The beginning of personalised medicine
(October 2002)
The SNP effort will serve as the bedrock of pharmacogenomics, the field of personalised medicine: the right drug, in the right dose, to the right person, at the right time
Surge in nucleic acid-based amplification
(June 2002)
Growing incidence of infectious diseases will inject vigour into the market for acid-based amplification kits, according to new market report
High throughput genotyping study
(April 2002)
Kiel University Hospital to investigate up to 2000 single nucleotide polymorphisms for associations with chronic intestinal inflammation, in particular Crohn's disease and ulcerative colitis