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Chemicals and biochemicals

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Supply chain improvements for medical testing labs

Products include buffers, cell culture reagents, histology stains, immunology reagents, laboratory equipment, molecular biology reagents, solvents as well as many others

News from Sigma-Aldrich (Europe) (23 September 2005)

Cell lines keep on growing

Rapidly and reliably determine the intracellular status of key signal transduction pathways upon exposure to drug candidates or other stimuli

News from Invitrogen Corporation (14 September 2005)

Bufferless gel now in SYBR-safe colour

SYBR safe stain is non-mutagenic, environmentally safe, may be used with a visible light-based imaging system, and provides virtually the same performance as their ethidum bromide counterparts

News from Invitrogen Corporation (14 September 2005)

Competent cells in a convenient format

Kit includes 20 pre-aliquotted cuvettes, each containing 25ul of electrocompetent E coli, one extra pre-aliquotted cuvette for a control transformation, SOC recovery coli media, and pUC19 control DNA

News from Invitrogen Corporation (14 September 2005)

Polymerase is a cost-effective alternative to Taq

DNA polymerase can be considered for use as a component in a diagnostic application if qualified by the end user, and does not carry the licensing restrictions, or costs, that Taq does

News from Invitrogen Corporation (14 September 2005)

New vectors are at the gate

Non-aggregating protein demonstrates successful performance in many fusions, including fusion with cytoplasmic beta-actin

News from Evrogen (12 September 2005)

Predesigned exon-specific oligonucleotide primers

Exon locator and extractor for resequencing streamlines the process of determining exon/intron boundaries and designing PCR and sequencing primers

News from MWG Biotech ( 9 September 2005)

A web of information on stains and dyes

 Technical background article   Online application provides interface for navigating staining procedures, catalogue information, product specifications, material safety data sheets, certificates of analysis and technical bulletins

News from Sigma-Aldrich (Europe) ( 8 September 2005)

Polymerase minimises levels of contaminating DNA

Contaminating DNA, present in most polymerase preparations, often precludes or obscures the accurate interpretation of results, especially when targeting conserved sequences

News from Sigma-Aldrich (Europe) ( 7 September 2005)

Medicinal chemistry services director appointed

Peakdale announces the appointment of 'industry figurehead' Terry Hart in order to drive further medicinal chemistry capabilities and enhance its range of services.

News from Peakdale Molecular (19 August 2005)

RNAi product line grows further

When completed, these shRNA clone libraries will comprise a comprehensive collection of 150,000 pre-cloned lentiviral-based shRNA vector constructs targeting 15,000 human genes and 15,000 mouse genes

News from Sigma-Aldrich (Europe) (10 August 2005)

Another GPCR library with more to come

This latest expansion of the company's Peakexplorer libraries is specifically designed, synthesised and characterised for screening against aminergic G-protein coupled receptor (GPCR) targets

News from Peakdale Molecular ( 9 August 2005)

High quality analysis of larger oligonucleotides

Sigma-Genosys has incorporated into its quality control (QC) lab an LC-MS system from Novatia to improve molecular weight determination of synthetic oligonucleotides and peptides

News from Sigma-Aldrich (Europe) (29 July 2005)

Licence to provide products and services in RNAi

Many diseases are caused by the inappropriate activity of specific genes, so the ability to silence and regulate such genes selectively could provide a means to treat a wide range of human diseases

News from MWG Biotech (27 July 2005)

shRNA libraries now in new format

Frozen bacterial glycerol stock format for lentiviral-based shRNA clones will save researchers time and expense in purifying transfection quality plasmid DNA

News from Sigma-Aldrich (Europe) (27 July 2005)

Next generation transcriptional reporter vectors

After transduction of the lentivector into mammalian cells, the construct becomes integrated into the cell genome and the reporter gene is expressed if the transcriptional factor is present

News from Cambridge BioScience (25 July 2005)

Sigma-Aldrich licences fundamental RNAi patent

Patent covers short interfering RNAs (siRNAs) and their use to mediate RNAi in mammalian cells

News from Sigma-Aldrich (Europe) (21 July 2005)

Now with in-house computational chemistry

Peakdale Molecular announces the establishment of its in-house computational chemistry expertise and the appointment of Steven Enoch to head the department and drive

News from Peakdale Molecular (20 July 2005)

New organisation to accelerate success and growth

Four new 'customer-centric' business units are called Essentials, Specialties, Biotech, and SAFC

News from Sigma-Aldrich (Europe) (14 July 2005)

Win prizes for histological strains

 Technical background article   Competition seeks best stained specimens on standard microscope slides, to encourage interest in the field of pathology and the science of staining

News from Sigma-Aldrich (Europe) (12 July 2005)

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