Product category:
Assay kits
News Release from: AnaSpec | Subject: EnzoLyte caspase assay kits
Edited by the Laboratorytalk Editorial
Team on 14 September 2006
HTS-optimised EnzoLyte caspase assay
kits
Caspase assay kits are optimised for high-throughput screening with features including one-step homogeneous assays, a convenient mix-and-read format, and highly sensitive fluorimetric components
Apoptosis, a programmed, cell-autonomous death process, plays important roles in a variety of physiological and pathological events These range from normal fetal development to diseases, such as cancer, organ failure and neurodegenerative diseases
This article was originally published on Laboratorytalk on 7 Jun 2006 at 8.00am (UK)
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Reagents kits for study of protein phosphorylation
Cellular phosphorylation is a reversible covalent modification of a protein or lipid that modifies the activity of the phosphorylated molecule by inducing conformational changes within the molecule
During apoptosis, caspases execute the disassembly of cellular components by proteolytic cleavage of a variety of substrates, such as poly-(ADP ribose) polymerase, DNA-dependent protein kinase (DNA-PK), topoisomerases, and protein kinase C delta4.
At least ten caspases have been discovered.
Some of these caspases identify and cleave a specific peptide substrate, while others recognize the same peptide substrate.
AnaSpec's line of EnzoLyte caspase assay kits are optimised for high-throughput screening.
HTS-optimized features include: one-step homogeneous assays, a convenient mix-and-read format, and highly sensitive fluorimetric components.
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