Product category:
Proteomics
News Release from: AnaSpec | Subject: Peptide products
Edited by the Laboratorytalk Editorial
Team on 11 October 2006
Calcium homeostasis: roles of PTH and
calcitonin
Calcium (Ca2+) plays a key role in numerous important physiological processes with the amount of ionised calcium in blood plasma tightly regulated within a narrow range
Calcium homeostasis is finely regulated by parathyroid hormone (PTH), calcitonin, and vitamin D Briefly, a decrease in calcium concentration in the blood, triggers the release of PTH, an 84-amino acid hormone, from the parathyroid glands
This article was originally published on Laboratorytalk on 15 Nov 2006 at 8.00am (UK)
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An increase, however, causes the release of Calcitonin, a 32-amino acid protein from the thyroid parafollicular cells (C-cells).
Vitamin D helps in the absorption of Ca2+ from the intestine.
AnaSpec, a provider of integrated proteomics, carries a wide range of peptide products to support researchers working with Ca2+ metabolism.
PTH (1-34).
Human, bovine, and rat - the amino-terminal PTH (1-34) fragment satisfies the structural requirements for all known biological activities of parathyroid hormone PTH(1-84)].
Biotinylated, FAM-labeled, and Lys-biotin-labeled - used as probes in studies such as characterisation of parathyroid hormone receptors.
Parathyroid hormone related protein (PTHrP).
1-34, 1-40, and 7-34 peptide fragments - responsible for most of humoral hypercalcemia of malignancy (HHM).
calcitonin.
Salmon, human, eel, and others.
Biotin-labelled and fluorescein-labelled.
Other calcitonin related peptides:.
CGRPs.
Adrenomedullins.
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