Product category:
Proteomics
News Release from: GE Healthcare | Subject: HiTrap Butyl-S FF
Edited by the Laboratorytalk Editorial
Team on 04 August 2005
Column purifies highly hydrophobic
proteins
These prepacked columns enable convenient purification or removal of highly hydrophobic proteins and offer different selectivities for small-scale media screening and purification
GE Healthcare has introduced HiTrap Butyl-S FF (1ml and 5ml) prepacked columns designed to meet the growing need for pure proteins in both research and process development HiTrap Butyl-S FF 1ml column is also included in the updated HiTrap HIC selection kit now expanded to six hydrophobic interaction (HIC) media with different selectivities for small-scale media screening and purification
This article was originally published on Laboratorytalk on 18 Apr 2003 at 8.00am (UK)
Related stories
Tips to improve radiochemical safety
Contains reaction-sized aliquots of radionucleotide in a solution-free format, making experiments easier and safer to do
20,000 human genes in a single experiment
Bioarray can be used to identify up or down regulated genes involved in key biological processes including oncogenesis, metabolism, inflammation and apoptosis
"The newest addition to the HiTrap HIC selection kit broadens screening of hydrophobic proteins and offers varying selectivities for optimal purification.
"This tools allows for fast, convenient screening to help researchers choose the most appropriate Sepharose HIC media when scaling up to the manufacturing level," said Allan Simpson, vice president of marketing research and analysis, protein separations at GE Healthcare.
"In a convenient, reliable format for fast and easy separations, the HiTrap columns provide highly reproducible results and consistent quality".
Further reading
Cassettes for high performance ultrafiltration
Help to speed up bioprocessing timelines by offering an easy way to separate, concentrate and diafilter biological solutions
Norak buys second cell analyser
Chooses additional In Cell analyser to support internal drug discovery programme and a new screening collaboration business
HiTrap Butyl-S FF is prepacked with Butyl-S Sepharose 6 Fast Flow, a hydrophobic chromatographic medium designed for purification of relatively strong hydrophobic molecules at low salt concentrations.
The medium is useful for removal of strongly hydrophobic contaminant because it is the least hydrophobic of GE Healthcare's HIC media.
The matrix Butyl-S Sepharose 6 Fast Flow is based on cross-linked agarose with a butyl ligand containing a sulphur atom, which means the ligand density can be accurately measured to secure reproducible production of the media.
With a flexible design, HiTrap Butyl-S FF can be used with a syringe, a simple laboratory pump or a chromatography system, such as Aktadesign or FPLC system.
GE Healthcare provides transformational medical technologies that it says will shape a new age of patient care.
GE Healthcare's expertise in medical imaging and information technologies, medical diagnostics, patient monitoring systems, disease research, drug discovery and biopharmaceutical manufacturing technologies is dedicated to detecting disease earlier and helping physicians tailor treatment for individual patients.
GE Healthcare offers a broad range of services to improve productivity in healthcare and enable healthcare providers to better diagnose, treat and manage patients with conditions such as cancer, neurological and cardiovascular diseases.
GE Healthcare is a $14 billion unit of General Electric, headquartered in the United Kingdom.
Worldwide, GE Healthcare employs more than 42,500 people committed to serving healthcare professionals and their patients in more than 100 countries.
• GE Healthcare: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page
Search the Pro-Talk network of sites
