Product category:
Chromatography accessories
News Release from: GE Healthcare | Subject: PreDictor plates, HiScreen columns
Edited by the Laboratorytalk Editorial
Team on 31 March 2008
Optimise chromatography for
bioseparations
GE Healthcare has launched a new range of PreDictor 96-well plates and HiScreen prepacked columns to enable high-throughput process development and method optimisation
GE Healthcare introduces PreDictor 96-well plates and HiScreen prepacked columns to improve process development efficiency The new products can be used independently, or as consecutive steps in a workflow to screen and optimise chromatographic conditions for bioseparations, thereby improving the efficiency of process development
This article was originally published on Laboratorytalk on 18 Apr 2003 at 8.00am (UK)
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PreDictor 96-well plates support high-throughput process development (HTPD) by allowing parallel screening of chromatographic conditions manually or in an automated workflow.
The plates, which are prefilled with GE Healthcare BioProcess media, enable fast and efficient evaluation of up to 96 chromatography conditions for binding, wash or elution with minimal sample and buffer consumption.
Data generated using PreDictor plates show good correlation with data obtained by column chromatography.
HiScreen columns are prepacked with a choice of 13 different BioProcess chromatography media, such as the different MabSelect and Capto media as well as five different hydrophobic interaction chromatography media based on Sepharose Fast Flow.
The columns are ideal for method optimization and parameter screening.
The 10cm bed height gives sufficient residence time to serve as a basis for linear process scale up and, if required, two columns can easily be connected in series to give 20cm bed height.
HiScreen columns are robust, can be used repeatedly with reproducible results for convenience and time saving.
GE Healthcare's BioProcess chromatography media have been specifically designed to meet the demands of industrial biotechnology.
The process chromatography media pass the rigorous selection requirements for the process scale downstream processing of biopharmaceuticals.
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