Product category:
Proteomics
News Release from: Bio-Rad Laboratories | Subject: MicroRotofor
Edited by the Laboratorytalk Editorial
Team on 24 July 2006
Enrich low-abundance proteins for
biomarkers
Biomarker discovery requires the ability to dig deeper into the proteome to find proteins that are of relatively low-abundance
Bio-Rad Laboratories has announced the capability of its MicroRotofor cell instrument to enrich low-abundance proteins for biomarker discovery Biomarker discovery requires the ability to dig deeper into the proteome to find proteins that are of relatively low-abundance
This article was originally published on Laboratorytalk on 13 Jul 2006 at 8.00am (UK)
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Enrich low abundance proteins, find biomarkers
Bio-Rad Laboratories has announced the capability of its MicroRotofor cell instrument to enrich low-abundance proteins for biomarker discovery
Bio-Rad announces use of MicroRotofor cell
Bio-Rad Laboratories has announced the use of its MicroRotofor cell for first-dimension protein separation
The effective study of low-abundance proteins often requires a fractionation step to reduce sample complexity and improve the concentration of low-abundance proteins.
With the MicroRotofor cell, formerly undetectable proteins can be enriched to levels that allow analysis by 2D gel electrophoresis/mass spectrometry (2D/MS) and liquid chromatography/tandem mass spectrometry (LC-MS/MS), methods that are commonly used in proteomics for the separation and identification of proteins.
The MicroRotofor cell is applied upstream of both 2D/MS and LC-MS/MS workflows.
The MicroRotofor cell is a preparative isoelectric focusing device that fractionates complex protein samples in free solution.
Whether used alone or as a part of a broader separation or purification scheme, the MicroRotofor cell offers rapid, simple, and effective fractionation and the enrichment of proteins from complex protein mixtures.
The majority of proteomics research, whether gel-based or another approach is used, requires fractionation to increase protein resolution for downstream experimentation.
The MicroRotofor cell fractionates by liquid-phase IEF, which is particularly beneficial for proteins that are insoluble or otherwise do not separate well in other, gel-based IEF media. Request a free brochure from Bio-Rad Laboratories ...
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