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Product category: Analytical, statistical and report generating software
News Release from: Bio-Rad Laboratories | Subject: KnowItAll v7.8
Edited by the Laboratorytalk Editorial Team on 03 April 2007

Knowitall enhancements now include
chemometrics

Bio-Rad Laboratories has announced the release of version 7.8 of its award-winning KnowItAll informatics system (Windows client)

The new release offers enhancements to many of the applications featured in prior versions of the KnowItAll platform including: Chemometrics models to predict properties based on spectral, chromatographic, and other data

This release highlights capabilities resulting from further collaborations with Infometrix, the premier chemometrics software company.

Chemometric models built with Infometrix' Pirouette software can now be imported directly into the KnowItAll platform.

These models can be used to make property predictions based on spectral, chromatographic, or other profile data.

They can predict a range of properties including biological, chemical, and manufacturing process-related endpoints.

All model types currently supported in Pirouette are supported in the KnowItAll system, including classification models (both single class and multiple class) and regression models (single property and multiple property).

Prediction confidence estimates are also supported.

Database projection analysis to identify 'markers' in a range of applications.

Another feature in the 7.8 release is the addition of Database Projection Analysis to KnowItAll's AnalyzeIt MVP application.

Database Projection Analysis is a tool for performing a more detailed analysis of the results from a Principal Component Analysis (PCA) that was run in the KnowItAll system.

Following PCA, Database Projection Analysis is performed by projecting a reference database, such as a suite of metabolite profiles or a Sadtler spectral database, into the space of the PCA results.

The unclassified samples can then be easily matched to known materials, facilitating the identification of relevant features or markers in the original data.

Database Projection Analysis has broad application in the field of chemometrics, including the direct identification of metabolites in metabolomics research.

Full data export/import capability with Infometrix Pirouette.

Bio-Rad's KnowItAll platform now supports full two-way export and import of data with Infometrix Pirouette software for comprehensive chemometric analysis and model construction.

The interoperability of the KnowItAll platform with Pirouette is a unique and complete solution for cheminformatic and chemometric data and model handling.

This technology pairing expands the options available to customers of both software packages by allowing them to seamlessly exchange data between systems, making the packages even more complementary.

Note that features will vary depending on the KnowItAll Informatics System edition being used and the software options elected by the KnowItAll researcher. Request a free brochure from Bio-Rad Laboratories ...

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