Product category:
Microfluidics/Lab-on-a-chip systems
News Release from: BlueGnome | Subject: CytoChip v2
Edited by the Laboratorytalk Editorial
Team on 06 September 2007
Higher-resolution v2 CytoChip now
validated
The Medizinisch Genetisches Zentrum in Munich, one of Germany's leading clinical laboratories, has completed the validation of BlueGnome's recently released version 2.0 CytoChip
The CytoChip is used in over 14 countries to investigate patients presenting with constitutional genetic disorders At just over half megabase resolution the v2 CytoChip offers a 50% increase over v1.1, with the majority of extra resolution focused on clinically important sub-telomeric regions
This article was originally published on Laboratorytalk on 7 Mar 2007 at 8.00am (UK)
Related stories
ArrayCGH results made easier to interpret
Following publication of a Nature paper, BlueGnome announced that all 3600 of the BAC clones on its v1.1 CytoChip have been validated against the results published by Redon et al
The v2 CytoChip is supported by a new release of BlueGnome's arrayCGH analysis software, BlueFuse for Microarrays, which has been optimised for use with the CytoChip.
Nick Haan, CEO of BlueGnome, explained: "As an open platform BlueFuse is required to make general assumptions about the microarray being analysed.
"However with the v2 CytoChip we took the opportunity to co-develop the content and layout of the chip with a new set of algorithms tailored for diagnostic applications".
Udo Koehler, head of cytogenetics, MGZ Munich, confirmed: "We have investigated over 200 patients using the v1.1 CytoChip and found it a very robust platform for clinical diagnostics.
"The combination of new the v2 CytoChips and BlueFuse algorithms will enable us to further enhance our service because, in contrast to conventional wisdom, we are able to increase the resolution of our investigations, while keeping interpretation simple and detection of polymorphisms to a minimum".
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