Product category:
Analytical, statistical and report generating software
News Release from: BlueGnome | Subject: CytoChip
Edited by the Laboratorytalk Editorial
Team on 30 October 2007
First US sales of CytoChip
BlueGnome reports that several laboratories have already switched to the CytoChip platform, a high resolution BAC microarray for the investigation of chromosomal abnormalities
With an overall resolution of just over 0.5Mb, and a focus on genomic regions known to be associated with genetic disorders, the CytoChip has proved to be much more informative than similar systems currently available in the United States, says BlueGnome As Karen Swisshelm, director of the Colorado Genetics Laboratory in Denver explained:, "When testing a 17p duplication case our existing commercial array detected only two non-consecutive clones whereas the CytoChip showed 22 clones, in the same region, as being duplicated
This article was originally published on Laboratorytalk on 7 Mar 2007 at 8.00am (UK)
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ArrayCGH results made easier to interpret
Following publication of a Nature paper, BlueGnome announced that all 3600 of the BAC clones on its v1.1 CytoChip have been validated against the results published by Redon et al
Accreditation for clinical use of microarrays
The Dutch Council for Accreditation (RvA) has accredited the array facility of the genome diagnostic section of the University Medical Centre Utrecht with NEN-EN-ISO 15189
"This increase in probe density and enhanced performance greatly improves both the confidence and ease of interpretation of the results".
Customer service has also proved important to laboratories moving forward with arrayCGH.
Maxine Sutcliffe, director, Cytogenetics and Molecular Cytogenetics and an associate professor of pediatrics at University of South Florida, Tampa, confirmed: "BlueGnome is clearly concerned about quality control issues and simplifying the protocols to be as cost effective as possible.
"Combined with a genuine desire to have an excellent product with excellent support this makes me feel very comfortable about switching platforms".
Nick Haan, CEO of BlueGnome, speaking at last week's American Society of Human Genetics meeting in San Diego explained: "We have encountered many laboratories that are keen to bring in house the processing of DNA samples that are currently sent out for analysis.
"For these people the complete solution; a high resolution BAC array, quality controlled consumables and labelled Fish probes backed by excellent technical support, enables them to significantly reduce their costs while providing a more responsive service".
The CytoChip is now used in over 19 countries to investigate copy number imbalance associated with constitutional genetic disorders.
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