Product category:
Laboratory and scientific databases
News Release from: BioFocus | Subject: Kinase Sarfari
Edited by the Laboratorytalk Editorial
Team on 12 June 2007
Focus on the protein kinase family of
drug targets
Kinase Sarfari enables users to design compounds and focused libraries against specific protein kinases and rapidly optimise compound discovery through exploration of structure-activity relationships
BioFocus DPI is launching its latest knowledge base, Kinase Sarfari, at this week's World Pharmaceutical Congress This fully integrated data repository and research workbench focuses on the protein kinase family of drug targets
This article was originally published on Laboratorytalk on 5 Sep 2007 at 8.00am (UK)
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It tool combines chemical and biological data from internal proprietary and public sources in a single, dynamic system.
Protein kinases are an important class of drug targets often pursued by the pharmaceutical industry because of the vital role they play in regulating cancer and inflammatory diseases.
Through effective integration and mapping of data from diverse biological and chemical sources, Kinase Sarfari increases productivity and enhances knowledge discovery, says BioFocus.
John Overington, senior director of discovery informatics at BioFocus DPI, said "The main advantage of Kinase Sarfari is the ability to integrate biological and chemical data from public and proprietary sources.
"The result is a powerful, single-sweep, data mining resource that provides unique insight on kinase drug discovery".
Overington will be presenting this new kinase drug discovery tool at this week's World Pharmaceutical Congress in Philadelphia, USA.
In the talk entitled 'Aligning target selection with compound design - leveraging prior knowledge for efficient discovery', he will discuss the value of integrating knowledge resources to facilitate effective drug discovery.
At the same conference, BioFocus DPI's senior director of target discovery, Richard Janssen, will deliver the presentation 'High content RNAi screen for huntington disease', where he will address the use of high content screens to identify genes that modulate the survival of cells over-expressing mutant forms of the Huntington protein.
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