Smart technology streamlines lyophilisation

Lyostat2 is a cutting-edge freeze-drying microscope enabling the quick and accurate identification of key parameters in your formulation, such as collapse, eutectic and glass transitions

Working freeze-drying cycles can be expensive to develop.

Many weeks or months of R+D can be spent developing a single cycle for a single formulation.

And once a working cycle is developed it is rarely altered- even though it may not be precise, making it inefficient.

Smart technology and the Lyostat freeze-drying microscope, working together, eliminate the time-consuming iterative approach to freeze-drying cycle development.

Lyostat2 offers real-time images of a product as it is freeze-dried, along with sample temperature and chamber pressure, all displayed on-screen for monitoring and analysis.

Plot information of temperature and pressure can be viewed, saved and exported to applications such as Excel for further investigation.

Once the critical temperatures of the formulation have been pinpointed with Lyostat, they are entered into the Smart system.

Smart freeze-drying technology from FTS Systems is described as a breakthrough tool that enables the process of developing lyophilisation cycles to be streamlined.

Data analysis on traditional freeze-drying cycles traditionally requires careful sampling and hours of detailed calculations.

With Smart, a unique feedback loop provides detailed data on the product and the cycle, freeing up scientist time and providing a data trail for regulatory compliance.

In typically just one or two development runs it can return a safe, optimised cycle, ready for scaling up to production.

The imprecise nature of conventional freeze-drying cycle development means many production cycles end up over-cautious and excessively long.

Smart and Lyostat together allow a streamlined cycle that can help shave days off your production cycle - expanding capacity and reducing production costs.

The Lyostat freeze drying microscope and Smart freeze drying technology (available on FTS Systems Lyostar freeze dryers) are both available in the UK and Ireland from freeze drying expert Biopharma Process Systems .

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