Product category:
Data management software
News Release from: CLC bio | Subject: Bioinformatics software
Edited by the Laboratorytalk Editorial
Team on 25 July 2006
NASA Chooses Sequencing Software from
CLC bio
The Exobiology Branch of the NASA Ames Research Center has chosen bioinformatics software from CLC bio for analysing sequencing data.
The Exobiology Branch of the NASA Ames Research Center in Moffett Field, California chose bioinformatics software from CLC bio for analysing sequencing data which revolves around hypersaline microbial mat systems that are found worldwide in exotic locations such as Baja, Mexico, and Solar Lake, Egypt, to name a few Exobiology - also known as astrobiology - is an interdisciplinary field, combining aspects of astronomy, biology and geology, which is focused primarily on the study of the origin, distribution and evolution of life
This article was originally published on Laboratorytalk on 30 Mar 2006 at 8.00am (UK)
Related stories
Bioinformatics software on Apple Intel computers
CLC bio announces that all its programs are Universal applications, and thereby supporting Apple's new Intel-based computers as from 16 March 2006
Four bioinformatics software releases from CLC bio
CLC claims to be the only company providing a full range of desktop based bioinformatics tools for Mac OS X, Windows, and Linux operating systems - including Apple's new powerful Intel-based computers
Microbial mat communities represent, in gross morphology, some of the earliest known microbial communities on Earth.
As a common form of microbial community existing on Earth during the Precambrian, and dominant in the Proterozoic era, these systems are hypothesised to have played a significant role in the development of modern oceanic and atmospheric conditions.
Dr Stefan J.
Further reading
World's first fully customisable bioinformatics
CLC bio has announced the release of its Software Developer Kit (SDK), called CLC Developer Kit, which will be a free add-on to all CLC bio's bioinformatics software products
Big updates to bioinformatics software workbenches
CLC bio releases major updates to its popular family of bioinformatics software workbenches, expanding the family with the brand new CLC RNA Workbench; free 30-day trial can be downloaded
Green, scientist from the Exobiology Branch of the NASA Ames Research Center, states: "We are currently employing various molecular tools to characterize shifts in community structure of the total microbial population as a result of alterations in sulphate and salinity levels".
"Our initial molecular analyses are performed using a fairly standard DNA extraction-PCR amplification-denaturing gradient gel electrophoresis (DGGE) methodology".
"We are employing a wide variety of primers for PCR-DGGE analyses and while many of these primer sets amplify regions of the 16 or 18S rRNA gene, we are also exploring a variety of primer sets to target functional genes".
"Such functional gene analyses can provide information regarding microbial function and phylogeny".
"CLC Combined Workbench is very useful in our manipulations of sequence data recovered from our exobiological analyses".
"In particular, the software has been useful in assembling complete and long gene sequences from multiple sequence reactions - with the sequencing trace visible for all overlapping reactions".
"For example, the dsrAB genes are approximately 1900 bp in length, and require a minimum of 3 sequencing reactions".
"The gene annotation feature is also highly beneficial, by helping establish, for example, where the dsrA gene ends and the dsrB gene begins, based on other sequences in Genbank".
"The wide variety of other tools in CLC's software are extremely useful - BLAST searches from within the program, in silico restriction digests, alignments, rudimentary phylogenetic trees, among a lot of other features".
"One of the worst facets of sequence analysis is the constant reformatting that must be performed to analyse the data with different programs - and with CLC's software the need for many of these manipulations are eliminated". Request a free brochure from CLC bio ...
"Thank you for creating such nice software!".
• CLC bio: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page
Search the Pro-Talk network of sites
