Product category:
Genomics
News Release from: Cambridge BioScience | Subject: Transit-TKO
Edited by the Laboratorytalk Editorial
Team on 28 January 2003
Knock out target gene expression
Transfection reagent enables simple and efficient short interfering (si) RNA-mediated gene silencing in a wide variety of cell lines
New Transit-TKO transfection reagent, now available from Cambridge BioScience, enables simple and efficient short interfering (si) RNA-mediated gene silencing in a wide variety of cell lines Mirus's Transit-TKO transfection reagent is the only reagent specifically designed to deliver siRNA to cells in vitro
This article was originally published on Laboratorytalk on 4 Apr 2003 at 8.00am (UK)
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Combined with the correct siRNA sequence against the target mRNA, Transit-TKO reagent can inhibit endogenous, stable or transient gene expression.
This novel reagent enables highly efficient siRNA transfection with minimal levels of cellular damage as compared to cationic-liposome based transfection reagents.
Transit-TKO transfection reagent is highly effective, allowing the use of extremely low levels of siRNA to successfully knock out both transient and stable gene expression in a wide variety of mammalian cell lines.
Also, because transfections are most effective when carried out in complete growth media, the use of Transit-TKO eliminates the need for a media change or addition of serum.
Transit-TKO delivery technology will enable the use of siRNA to inhibit expression of endogenous cellular genes in order to study a wide variety of biological phenomena.
Gene function can be investigated by assessing the biological effects of siRNA-mediated knock out of expression of that particular gene.
These products are available from Cambridge BioScience in the UK and Ireland only.
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