Product category:
Proteomics
News Release from: Cambridge BioScience | Subject: Multiplexed Proteomics
Edited by the Laboratorytalk Editorial
Team on 20 August 2003
Novel proteomics platform
Multiplexed approach simplifies the identification of changes in expression, post-translational protein modification in the form of phosphorylation, and glycosylation
Molecular Probes has launched Multiplexed Proteomics, a radical new platform that facilitates comprehensive proteome analysis It allows the direct detection and quantitation of total and specific proteins in the same gel, using reagents that have contrasting colours
This article was originally published on Laboratorytalk on 4 Jul 2005 at 8.00am (UK)
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Multiplexed Proteomics technologies are available through Cambridge BioScience.
Traditionally, polyacrylamide gel electrophoresis and related blotting techniques have been the core methods for protein analysis and silver staining has been the leading non-radioactive visualisation technique for very low protein levels.
Advances in proteomics research have brought the need for high throughput techniques.
This has exposed the limitations of absorption-based technologies and has driven the development of fluorescence and luminescence-based protein detection.
The Multiplexed Proteomics platform brings together Molecular Probes's new phosphoprotein stain Pro-Q Diamond; Sypro Ruby protein stain; and Pro-Q Emerald glycoprotein stains.
Each is a powerful reagent in its own right.
When acting in combination they enable the simultaneous detection of multiple protein targets, in a single sample, on the same gel.
This allows more data to be collected from precious samples.
The Multiplexed Proteomics approach simplifies the identification of changes in expression, post-translational protein modification in the form of phosphorylation, and glycosylation.
It also allows the accurate and reproducible comparison of multiple samples.
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