Product category:
Chemicals and biochemicals
News Release from: Cambridge BioScience | Subject: Rabbit anti-synaptophysin
Edited by the Laboratorytalk Editorial
Team on 08 April 2004
Rabbit anti-synaptophysin for in vitro
diagnostics
Can be used for qualitative differentiation between neuroendocrine and non-neuroendocrine neoplasms performed on either frozen or formalin-fixed paraffin embedded tissue sections
Cambridge BioScience has added rabbit anti-synaptophysin from Zymed Laboratories to its extensive range of antibodies Intended for in vitro diagnostic use, anti-synaptophysin can be used for qualitative differentiation between neuroendocrine and non-neuroendocrine neoplasms
This article was originally published on Laboratorytalk on 4 Jul 2005 at 8.00am (UK)
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This is performed on either frozen or formalin-fixed paraffin embedded tissue sections using light microscopy.
Synaptophysin is a 38 kDa glycosylated peptide that was initially isolated from presynaptic vesicles of neurons.
It is the major transmembrane protein of synaptic vesicles and is ubiquitously expressed throughout the brain.
In a recent study, the synaptophysin antibody demonstrated immunoreactivity in 93% of neuroendocrine tumours demonstrating its usefulness in detecting neoplasia of neuronal and neuroepithelial differentiation.
These products are available from Cambridge BioScience in the UK and Ireland only.
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