Product category:
Optical microscopes
News Release from: Carl Zeiss MicroImaging | Subject: Colibri LED light source
Edited by the Laboratorytalk Editorial
Team on 09 August 2007
Narrow light band LEDs enhance
fluorescence images
Carl Zeiss MicroImaging has introduced the Colibri, a patented high-performance, Light Emitting Diode (LED) light source for fluorescence microscopy
The company holds the exclusive North American licence to distribute the technology The narrow band LEDs replace conventional white light sources to produce extremely high contrast images with an excellent signal-to-noise ratio, enabling the detection of weak signals and fine details in applications ranging from routine biomedical research to complex live cell imaging
This article was originally published on Laboratorytalk on 4 Apr 2003 at 8.00am (UK)
Related stories
Contrast enhancement for 3D imaging
3D imaging system for contrast enhancement in fluorescence microscopy based on innovative grid projection technique permits high quality optical sections to be roduced quickly
When 3D microscopy isn't enough
3D fluorescence imaging taken to a new dimension with software to enable viewing in time, opening up new insights into biological functions and interrelations
The intensity of the narrow-band LEDs can be quickly and accurately set for any wavelength and exactly adapted to the specimen, therefore ensuring maximum protection.
As the switching procedure is purely opto-electronic, there is no motion or vibration that could impair image quality in high speed time series experiments.
With Colibri it is possible to switch excitation wavelengths in micro seconds.
Minimised heat build-up also results in more stable conditions during experiments.
This makes Colibri ideal for working with sensitive living cells, but also offers numerous enhancements for fluorescence microscopy with fixed specimen.
A selection of four LEDs can be used individually, sequentially or simultaneously with any intensity setting, which is particularly helpful in balancing intensities of the various fluorescence channels.
Due to its innovative design, Colibri offers high flexibility: ten different wavelengths from UV to dark red are currently available.
Further advances of the rapidly developing LED technology, like new wavelengths or higher emissions, can therefore be implemented quickly and without complication by the customer.
The LED modules are equipped with automatic component recognition (ACR) and automatically recognised by the system, ruling out the possibility of incorrect operation.
A motorised switching capability to a fibre-optically coupled white metal halide light source is integrated to add flexibility.
Colibri can be operated as a stand-alone unit or upright and inverted with manual or motorised microscopes, but can also be controlled with the basic version of Zeiss AxioVision software without additional cost.
• Carl Zeiss MicroImaging: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page

