Product category:
Mechanical testing equipment
News Release from: Copley Scientific | Subject: Critical Flow Controller TPK 2000
Edited by the Laboratorytalk Editorial
Team on 28 March 2007
Flow controller for dry powder inhaler
testing
Critical Flow Controller TPK 2000 is designed to control and document all the critical parameters associated with dose uniformity and cascade impactor testing for dry powder inhalers (DPIs)
Based on Copley Scientific's original TPK critical flow controller, now widely recognised as an industry standard, the TPK 2000 offers significantly enhanced functionality including an RS232 interface, menu driven operation and environmental condition measurement The US and European Pharmacopoeias (USP and Ph Eur) specify that flow rate, total air volume and flow stability must be carefully controlled during DPI testing
This article was originally published on Laboratorytalk on 13 Feb 2007 at 8.00am (UK)
Related stories
New product at APS Inhalation 2007
Copley Scientific is a major sponsor of the forthcoming Association of Pharmaceutical Sciences Inhalation 2007 meeting in Bath (UK) 27-28 March, and will exhibit for both days at the event
Spray force tester for nasal sprays and MDIs
New Copley Spray Force Tester SFT 1000 for nasal sprays and MDIs reflects growing importance of impaction force in characterising pharmaceutical sprays
Flow rate must be manipulated to generate a 4 kPa pressure drop across the DPI, up to a maximum flow of 100l/min, with the duration of flow controlled to give a total air volume of two or four litres.
Critical flow across the flow control valve is also required to minimise flow rate instability.
The TPK 2000 makes test set-up easy in line with these specifications.
A user-friendly interface provides guidance through the testing procedures specified by the pharmacopoeias.
Following an initial set-up procedure, which identifies the air flow rate required for testing based on the flow resistance of the device, the TPK 2000 automatically measures and/or calculates all required variables including,test flow rate and ambient conditions - air pressure, temperature and relative humidity - as well as monitoring critical flow.
These parameters along with system calibration data can be printed or exported via RS232 (or USB).
An optional interface with Copley's flow meter model DFM 2000 permits volumetric air flow rate measurement during the set-up routine, simplifying and accelerating this part of the procedure.
Utilising two external pressure taps the TPK 2000 can also be used to determine leak rates and total pressure drops for both Next Generation and Andersen Cascade Impactors; valuable data for monitoring day-to-day impactor performance and suitability.
The TPK 2000 is designed for user calibration within the lab environment.
• Copley Scientific: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page
Search the Pro-Talk network of sites
