Product category:
Mechanical testing equipment
News Release from: Copley Scientific | Subject: Friabimat SA-400
Edited by the Laboratorytalk Editorial
Team on 06 March 2008
Friability tester tackles the hardest
dosage forms
The new Friabimat SA-400 from Copley Scientific uniquely delivers friability testing for even the hardest, most robust solid dosage forms
The use of the Friabimat SA-400 is detailed in Chap 2.9.41 (Method B) of the European Pharmacopoeia, which came into effect on 1 January 2008 With tests taking an average of just two to four minutes, the system is suitable for both QC and research applications
This article was originally published on Laboratorytalk on 13 Feb 2007 at 8.00am (UK)
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For some hard coated and uncoated tablets, granules and spheroids, it is impossible to determine friability using conventional drum testers, even with significantly extended test times.
The Friabimat SA-400, a small footprint unit originally designed for testing granules and pellets, is ideal for such materials.
Sample is shaken within a glass vessel, in the horizontal plane, by means of an oscillating arm that operates at a defined rate.
Particles rub against and collide with one another and/or the vessel walls, causing friability and abrasion.
Varying the speed, in the range 0-400 oscillations per minute, controls abrasion intensity, and the test time can be set from 0-9999 seconds.
Such close control makes it easy both to optimise testing procedures and ensure the reproduction of identical test conditions.
Relatively short test times, coupled with the use of standardised, inexpensive sample containers makes routine testing extremely cost-effective.
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