Visit the Genevac web site
Click on the advert above to visit the company web site

Product category: Evaporation equipment
News Release from: Genevac | Subject: Centrifugal evaporation technical report
Edited by the Laboratorytalk Editorial Team on 08 July 2004

Purification of drug-like compounds

Technical report demonstrates how automated centrifugal evaporation system compares favourably with traditional rotary evaporation in the separation and recovery of drug-like molecules

A new independent technical report is available from Genevac, demonstrating how an automated centrifugal evaporation system compares favourably with traditional rotary evaporation in the separation and recovery of drug-like molecules Today, many drug discovery chemists seek to purify compounds by adsorbing a mixture of compounds on a small amount of silica and 'dry-load' the mixture onto a column prior to chromatography

The classical method of adsorbing compounds onto silica in a round-bottomed flask and then removing solvent using a rotary evaporator is limited by its slow throughput, lack of automation and loss of sample due to 'bumping'.

The new technical report details how centrifugal evaporation technology successfully addresses each of these issues to provide an attractive automated alternative method for dry loading samples prior to chromatography.

In addition the technology offers similar benefits for work-up of parallel synthesis reactions, where it offers a combinatorial method of dry loading to streamline the parallel purification process.

For a copy of this technical paper please contact Genevac. Request a free brochure from Genevac ...

Genevac: contact details and other news
Email this article to a colleague
Register for the free Laboratorytalk email newsletter
Laboratorytalk Home Page

Search the Pro-Talk network of sites

Visit the Genevac web site