Product category:
General lab equipment
News Release from: Hugo Sachs Elektronik | Subject: Isolated heart systems
Edited by the Laboratorytalk Editorial
Team on 23 February 2007
Heart platforms allow on-line transition
All Hugo Sachs Elektronik dedicated isolated heart systems allow on-line transition between langendorff and working heart perfusion
While the long-standing Langendorff (LH) mode of isolated heart perfusion has indisputable utility as a cardiac research tool, it is becoming increasingly clear that many desirable assays require the ejecting capability of an organ perfused in the working heart (WH) mode Inarguably, a more physiologically relevant configuration, WH mode provides the ability to monitor the activity of a heart performing pressure-volume work
This article was originally published on Laboratorytalk on 4 Oct 2006 at 8.00am (UK)
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New Langendorff isolated heart system
The basic Langendorff isolated heart systems (BLIHS) are ready to use isolated heart perfusion systems for rodent hearts such as mouse, rat and/or guinea pig
A defining characteristic of all Hugo Sachs Elektronik dedicated isolated heart systems is the ability to switch between LH and WH operation, online, in the same heart, with just a few simple manipulations.
In addition, both modes can be maintained using either constant flow or constant pressure perfusion.
Furthermore, physiological cardiac afterload is maintained using an exclusive, patented flow resistance and compliance chamber.
These advanced features and forward-looking design are available in research platforms optimised for all commonly used mammalian research models.
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