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3D cell culture is more like human body

An Invitrogen product story
Edited by the Laboratorytalk editorial team Jul 16, 2007

Invitrogen has announced the launch of the Gibco AlgiMatrix 3D culture system, an animal-origin free bioscaffold that more closely mimics the conditions of a cell in the human body

The Gibco AlgiMatrix 3D culture system provides superior cell loading, nutrient delivery and potential for cell-to-cell interaction.

"AlgiMatrix meets the growing demand in cell culture to replace two-dimensional culture dishes with 3D scaffolds," said Nicolas Barthelemy, Invitrogen's senior vice president, cell culture systems.

"This scaffolding better mirrors the environment experienced by normal cells in the body, and enables inter-cellular interactions with more realistic biology and functional relevance".

"AlgiMatrix is suitable for many cell-based screening, drug discovery, and human cell therapy procedures".

Unlike animal-derived 3D matrices, Algimatrix, a macroporous alginate sponge structure, delivers more consistent results to support the growth of diverse cell types.

It is also available at room temperature.

AlgiMatrix is the latest offering from Invitrogen as part of a growing product portfolio in the cell culture system business.

Recently, the company acquired Cascade Biologics, a company with expertise in the development and manufacture of primary cells and specialised media and supplements.

The company's objective is to provide next-generation cell culture systems that serve specific disease-focused research sectors with tailored solutions.

"Cell biology involves so much more than keeping cells alive in the lab.

"It requires cell characterisation and monitoring throughout the experiment, and sensitive assay readouts for meaningful scientific results.

"By combining our cell culture capabilities with labeling and detection technologies from our Molecular Probes subsidiary, we believe we can offer our customers complete solutions for conducting better, more complete research into the biology of cells," Barthelemy said.

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