Product category:
Mass spectrometers
News Release from: Ionalytics
Edited by the Laboratorytalk Editorial
Team on 13 November 2003
Collaboration on Maldi/Faims research
Project investigates atmospheric pressure laser desorption techniques in combination with high-field asymmetric waveform ion mobility spectrometry to boost mass spectrometers
Ionalytics, developer of analytical instruments for the proteomics and pharmaceutical industries, and researchers at the University of Florida (UF) have announced they will collaborate on a research project to investigate the use of atmospheric pressure laser desorption (LD) techniques in combination with high-field asymmetric waveform ion mobility spectrometry (Faims) to boost performance of mass spectrometers Richard Yost, professor of chemistry at UF, will lead the research group
This article was originally published on Laboratorytalk on 2 Apr 2004 at 8.00am (UK)
Related stories
Ion mobility front-end for mass spectrometry
Aftermarket mass spectrometry accessory that yields reduced chemical background, increased selectivity, and improved detection limits will be marketed for LC/MS and LC/MS/MS systems
Radiometer/spectroradiometer products on show
Able Instruments and Controls will be displaying the full range of light measurement equipment available from International Light at the 2004 Photonex Exhibition
On your marks
Industrial marking equipment supplier buys developer of two-dimensional code reading and machine vision solutions
Specifically, the team will investigate ways to interface LD techniques, such as atmospheric pressure/matrix-assisted laser desorption ionisation (AP/Maldi) and laser desorption/atmospheric pressure chemical ionisation (LD/APCI) with the Ionalytics Selectra, a dynamic ion-filtering instrument based on Faims.
Roger Guevremont, founder and chief scientific officer at Ionalytics, will also collaborate on the research.
The Selectra provides an additional dimension of ion separation, resulting in reduced chemical background noise, separation of some isobaric interferences, and improvements in detection limits.
By combining Faims and LD techniques, the team hopes to decrease chemical background noise, currently one of the major problems limiting the sensitivity of LD techniques.
The result will be improved spectra and better detection of low abundance compounds, including proteins.
The Yost group's research interests are in analytical mass spectrometry, particularly tandem mass spectrometry.
He and his research group (totaling over 60 graduate students in the past 20 years, with funding totaling nearly US$6 million) are currently focusing their efforts on ion trap MSn and on high-field asymmetric waveform ion mobility spectrometry, including design of new instrumentation, fundamental studies and applications.
"The University of Florida's analytical chemistry department is widely regarded as one of the top few such programmes in the world.
"They have been studying Faims for the past year and now we're pleased to be working with them, using the Selectra," said Dr Guevremont.
"The collaboration provides an opportunity to further explore Faims with laser desorption, which we hope will lead to improved techniques for both research laboratory and commercial applications.".
• Ionalytics: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page
Search the Pro-Talk network of sites
