Product category:
Particle size analysis equipment
News Release from: Malvern Instruments | Subject: Spraytec
Edited by the Laboratorytalk Editorial
Team on 07 September 2005
Particle size analysis of aerosols and
sprays
Laser diffraction-based system tackles the highly challenging task of the analysis of sprays, which can be wet, messy, and transient
Malvern has launched a new generation Spraytec system for particle size analysis of aerosols and sprays Like its ground-breaking predecessor, the new Spraytec delivers fully automated in situ analysis of high concentration aerosols and sprays from a robust platform, but has a data acquisition rate four times faster, covers more than double the size range, is driven by standard operating procedures that allow single click operation, and (most importantly) has a sleek new look
This article was originally published on Laboratorytalk on 24 Jun 2008 at 8.00am (UK)
Related stories
Melbourn is first UK CRO to routinely use Spraytec
Melbourn Scientific has become the first CRO in the UK to routinely use the Malvern Instruments Spraytec particle size analyser to support the development of inhaler, nebuliser and nasal spray systems
Aiming to make vaccine delivery pedal-powered
Researchers at Aerovax, at MIT, are using the Spraytec particle size analyser from Malvern in the development of an innovative platform for vaccine delivery, intended for use in developing countries
Particle size in sprays and aerosols is important in defining product performance in a range of applications, from the delivery of pharmaceutical formulations through to the application of coatings and agrochemicals, and the development of fuel injection systems.
However, sprays can be wet, messy and are often transient, making their analysis highly challenging.
Malvern's laser diffraction-based Spraytec system is an established tool for particle size analysis in sprays, delivering real-time, high-speed measurements that enable the complete characterisation of both continuous and pulsed events.
Further reading
Spraytec aids dry powder inhaler development
At 2008's Respiratory Drug Delivery conference, a poster from Malvern Instruments and David Morton describes the Investigation of Powder Dispersion from a Dry Powder Inhaler Using Laser Diffraction
Data capture and processing extended on Spraytec
Spraytec uses the technique of laser diffraction to measure spray particle size distributions and is widely used for the analysis of a wide range of industrial and pharmaceutical aerosols and sprays
The new Spraytec has an increased data acquisition rate of 10kHz, which means a 100-microsecond time resolution, allowing extremely accurate analysis of the dynamics of spray atomisation and dispersion: even the rapid changes in particle size that take place in pulsed spray events such as fuel injector operation can be followed precisely.
An extended size range from 0.1 to 2000 microns, using just two lens systems, enables the routine characterisation of broad size distributions, with a dynamic range of more than 1000:1 covered by each lens.
Malvern's patented multiple scattering analysis additionally ensures accurate measurements at high spray concentrations, where it says traditional laser diffraction systems would fail.
Spraytec's unique optical design, efficient air purging, and the ability to use a range of optical bench sizes overcome the physical challenges of measuring dense, widely distributed sprays and allow the continuous operation necessary for meaningful measurement and analysis.
The robustness and simple operation of the Spraytec are important factors in its continued success and both are evident in the new system, from the design of the optical bench through to its software implementation.
Automatic alignment ensures fully optimised system set up.
A built-in SOP wizard aids method definition and transferability, and gives single-click operation.
Measurements can be followed in real time.
For use in regulated environments, full lifecycle documentation, following GAMP guidelines, provides complete design traceability; IQ/OQ documentation is provided for validation plans; and software provides technical compliance with the requirements of 21 CFR Part 11. Request a free brochure from Malvern Instruments ...
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