Product category:
Chemicals and biochemicals
News Release from: Millipore | Subject: Tyrosine kinases with BioForm technology
Edited by the Laboratorytalk Editorial
Team on 19 December 2007
A better environment for cell signalling
Millipore's Tyrosine kinases with BioForm technology can be used in many key stages of drug discovery, including early stage drug screening, signal transduction and regulation of enzymatic activity
Millipore has launched its Tyrosine kinases with BioForm technology developed by PA Technologies in Amherst, MA The coupling of the technology and select Millipore Tyrosine kinases provides a better, more biologically relevant environment for cell signaling research and discovery efforts
This article was originally published on Laboratorytalk on 3 Jul 2008 at 8.00am (UK)
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Conventional analysis of membrane protein signaling involves studying a single protein interacting with a single partner.
Such analysis loses rich, two-dimensional information afforded by organisation of proteins on the membrane surface.
BioForm Technology enables the unique assembly of histidine-tagged proteins in an environment that mimics that created by a cell membrane.
This template restores the organising features of the membrane without the difficulties of membrane preparation and reconstruction procedures.
The technology is adaptable to high throughput assay format and is applicable to many signaling systems.
Additionally, this new kinase assay platform may be used for functional in vitro assembly of multiple protein targets.
Established in 1954 as a high performance filtration products and services company, Millipore has grown into a partner for life science customers through R+D investment, organic growth and acquisitions.
Companies acquired include Chemicon, Upstate, Linco and NovAseptic. Request a free brochure from Millipore ...
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