Product category:
Genomics
News Release from: Nextgen Sciences | Subject: Optigel
Edited by the Laboratorytalk Editorial
Team on 15 September 2006
Precast gels offer reproducibility and
ease of use
NextGen Sciences has launched a new range of Optigel high performance, large format, pre-cast 2D gels available in a choice of gradients and supports
Developed for customers who require definitive separation performance and reproducibility, Optigels are available with either standard or low fluorescing glass plates to allow compatibility with both traditional and fluorescent labelling systems 2D gel electrophoresis has become an increasingly important tool for the analysis of complex multi-protein samples
This article was originally published on Laboratorytalk on 8 Dec 2003 at 8.00am (UK)
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The major drawback of this system, which precludes universal acceptance of this technique has been the variability seen between gels, even those manufactured on the same day in the laboratory.
The introduction of the a2DEoptimizer from NextGen offered customers a way to solve variability issues but was only really economic where the laboratories were casting large numbers of gels.
With the launch of its customisable gradient pre-cast optigels, NextGen has overcome these hurdles and can now make this invaluable analytical tool available to all laboratories large and small.
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System automates gel casting to user-defined gradients, eliminating the variability and expense of hand-poured gels along with their short shelf lives
Manufactured using NextGen Sciences proprietary a2DEoptimizer automated gel casting system, Optigels offer unmatched gel to gel and batch to batch reproducibility combined with the improved performance benefits of acrylamide gradients and the convenience of a pre-cast gel.
"The company has identified a significant niche in the research market where reproducibility is key" commented James Heffernan, CEO of NextGen.
"Where large numbers of gels are used it makes sense to buy the a2DEoptimizer in order to get the level of consistency and performance from 2D gel electrophoresis that is expected.
"However where small numbers of gel plates are required and accuracy and consistency is paramount, we can now offer all laboratories access to the best pre cast 2D gels available today" he added.
Customers who require unique protein separation conditions can also take advantage of a custom-gradient design service, available with 48 hour turnaround and at no additional cost compared to a standard pre-cast gel.
Orders for catalogue gels will be dispatched within 24 hours.
Commenting further Heffernan said: "Independent studies across multiple gels, separate casting instruments and on different days, with a wide range of protein markers have yielded an average CV (variability) of only 3.4% across all of the gels produced.
"This is a result only previously wished for in the 2D gel market.
"It can now be the norm, with Optigels becoming the gold standard in 2D gel separations".
To help the customer choose the optimal gradient for their sample the company has launched small trial kits containing different linear gradients.
Once the customer has determined which gradient works best for them, they can order in bulk with the assurance of gel to gel comparability, or can still choose to use a completely customised gradient prepared by NextGen all for the same price.
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