Single step laser microdissection
A
Nikon UK product story
Edited by the Laboratorytalk editorial team
Nov 1, 2004
Fully automated UV dissection system allows users to view samples on screen and outline areas of interest, and to dissect and safely isolate these cells for further PCR extraction
Following the recent agreement with Molecular Machine and Industries (MMI), to sell its cell manipulation products, the MMI Cellcut laser microdissection system is now available from Nikon Instruments.
This represents a fully automated UV dissection system that, when coupled to video imaging on the Eclipse TE2000, allows users to view samples on screen and outline areas of interest using the mouse or screen pen, and to dissect and safely isolate these cells for further PCR extraction.
Ideal for scientists working with or wishing to extract DNA, RNA and/or proteins, this reliable, precise and contamination free system uses cold UV laser technology, meaning samples are not exposed to additional heat or radiation that could damage cells.
The system provides the perfect platform to perform live cell cutting and cell transfer from existing or archived slides, even if frozen.
Cellcut automatically cuts the sample, measures cell dimensions, determines the area, and documents the event.
An overview image of the entire sample is provided on screen as a reference point for easy navigation.
Furthermore, Nikon's TE2000E computer optimised optics and a high precision stage ensures accurate positioning, better than one micron.
Isolated samples are securely removed using a new adhesive membrane, which protects the tissue on the slide against cross contamination.
A single step collection picks up only dissected cells for further processing.
The samples are collected in the same orientation as on the intact sample - so that positions can be verified, if needed.
In contrast to some other microdissection systems the samples are fixed at all times - there are no loose or falling samples.
MMI's Cellcut system comes complete with powerful software that memorises the set up for each lens on the microscope ensuring the correct focus and laser power.
This also enables precise delineation of the cutting path - including the cutting of multiple samples.
Not what you're looking for? Search the site.
Contact Nikon UK
Tel +44 208 24717 18
Other Nikon UK stories
-
Mi Macro Station analyses tissues in cut-up rooms
Nikon has released the Mi Macro Imaging Station, which can safely capture, annotate and measure images of fixed and unfixed tissues in the mortuary or pathology laboratory. -
Nikon kits out pathology lab
The Mid Yorkshire Hospitals NHS Trust has fitted out its state-of-the-art pathology building with digital imaging and microscopy equipment from Nikon. -
Nikon instruments used in embryology MSC course
The University of Oxford has developed an intensive one-year residential taught MSC course in clinical embryology, supported by a range of Nikon equipment and instruments. -
Nikon to distribute specimen preparation products
Nikon Instruments Europe and Slee Medical have announced a distribution partnership that appoints Nikon as the official European distributor of Slee's pathology specimen preparation equipment. -
Nikon's PFS comes second in The Scientist awards
Nikon Instruments' Perfect Focus System (PFS) has been ranked second in The Scientist's top innovations of 2008.
Articles by product category
-
Analytical instruments (8,805)
- Analytical instruments (13)
- Chemical analysis equipment (631)
- Chromatographs: gas (241)
- Chromatographs: liquid, ion, gel, HPLC (427)
- Chromatography accessories (503)
- Gas analysis equipment (219)
- pH and conductivity meters (114)
- Cameras and imaging systems (820)
- Electron microscopy systems (209)
- Optical microscopes (448)
- Microscope supplies and accessories (558)
- Mass spectrometers (458)
- Spectroscopy (535)
- Other analytical instruments (592)
- Particle size analysis equipment (555)
- Microplate readers (39)
- Temperature, pressure and flow measurement (262)
- Spectrophotometers (273)
- Titration equipment (655)
- Ultrasound equipment and ultrasonic spectroscopy (118)
- Viscometers and rheometers (346)
- Oscilloscopes (83)
- Mechanical testing equipment (492)
- Test and calibration instrumentation (214)
-
Life sciences and clinical laboratory equipment (3,579)
- Life sciences and clinical laboratory equipment (3)
- Clinical chemistry analysis (898)
- Nucleic acid sequencing and synthesis (637)
- Genomics (459)
- Proteomics (450)
- Assay kits (185)
- Microbiology (383)
- Polymerase chain reaction (PCR) (240)
- Cell/tissue handling and counting (324)
-
Computer hardware (826)
- Computer hardware (7)
- Dataloggers (302)
- I/O devices (362)
- Monitors and peripherals (50)
- Process control and networking (79)
- PLCs (26)
-
Industry news (19)
- Industry news (19)
-
Laboratory equipment and wares (5,937)
- Laboratory equipment and wares (5)
- Safety and ventilation equipment (322)
- General lab equipment (831)
- Workstations (61)
- Detectors, sensors and probes (375)
- Lab automation equipment and robotics (651)
- Laboratory furniture and storage (151)
- Gas handling (125)
- Heating: ovens, furnaces, autoclaves (331)
- Fermentation and incubation equipment (73)
- Microplates/microarrays and readers (397)
- Microfluidics/Lab-on-a-chip systems (142)
- Distillation equipment (16)
- Sampling equipment (156)
- Environmental chambers (88)
- Fume cupboards ductless (79)
- Laboratory glassware (400)
- Liquid handling (415)
- Cooling: refrigeration (198)
- Washing and sterilisation equipment (207)
- Fume cupboards ducted (31)
- HTS and combinatorial chemistry equipment (57)
- Evaporation equipment (166)
- Weighing and balancing (240)
- Centrifuges (47)
- Water purification (213)
- Laboratory plasticware (160)
-
Laboratory supplies and consumables (1,271)
- Laboratory supplies and consumables (2)
- Culture media (119)
- Reagents and catalysts (169)
- Antibodies (203)
- Cleaning products (65)
- Reference standards (178)
- Chemicals and biochemicals (534)
-
Pumps, Valves, Filters (708)
- Automated Valves (66)
- Filtration equipment and supplies (176)
- Metering pumps (109)
- Other pumps (63)
- Peristaltic pumps (65)
- Vacuum pumps and compressors (144)
- Manual Valves (85)
-
Services (2,989)
- Contract research (889)
- Laboratory and scientific exhibitions and conferences (230)
- Laboratory and scientific recruitment (26)
- Laboratory and scientific consultancy services (288)
- Laboratory and scientific training and education (413)
- Laboratory building and design (50)
- Laboratory and scientific manufacturing services (136)
- Laboratory and scientific professional organisations (482)
- Laboratory and scientific books and publishing (475)
-
Computer software (2,882)
- Computer software (4)
- Chemical modelling software (181)
- Laboratory and scientific databases (327)
- Instrument control software (320)
- Laboratory information management system (LIMS) (721)
- Mathematical software (163)
- Process control and networking software (52)
- Data acquisition software (171)
- Chromatography software (284)
- Spectroscopy software (92)
- Analytical, statistical and report generating software (284)
- Data management software (283)
