Product category:
Antibodies
News Release from: Meridian Life Science | Subject: BSA, T7, HA, etc antibodies
Edited by the Laboratorytalk Editorial
Team on 01 September 2006
Antibodies produced in chickens
The chickens are immunised and antibodies are purified from the eggs; a single hen can lay enough eggs to produce up to 3g of IgY per month, 10-20 times the amount of IgG produced from a rabbit
Biodesign International/OEM Concepts has expanded its product offering for antibodies produced in chickens Specificities offered include: BSA, T7, HA, etc, as well as a chicken antibody-based Protein A Elisa Kit
This article was originally published on Laboratorytalk on 16 Sep 2002 at 8.00am (UK)
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Improved Hama blocking reagent
As this reagent is used at a much lower concentration to achieve the same blocking efficiency, serum matrix effects are minimised or eliminated
Some advantages of using chicken antibodies include: 1) chickens are not mammal, therefore more likely to produce high affinity antibodies to mammalian antigens; 2) using chickens is a more humane way to produce antibodies.
There is no need to bleed the chickens.
The chickens are immunised and antibodies are purified from the eggs.
Bulk production capabilities: a single hen can lay enough eggs to produce up to 3g of IgY per month, which is 10-20 times the amount of IgG produced from a rabbit.
The Fc region of chicken IgY is different from mammalian IgG, thus reducing background by not binding to mammalian rheumatoid factors (RF) or human anti-mouse antibodies (Hama).
Lower cost: compared to rabbit or goat, it is more cost-effective to produce chicken antibodies in bulk.
Chicken antibodies do not bind to Staphylococcal Protein A and Streptococcal Protein G, therefore are widely used in Protein A and Protein G Elisa assays.
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