Product category:
Chemicals and biochemicals
News Release from: Otava | Subject: 2-arylsylfonyl-2-hetarylethylamines
Edited by the Laboratorytalk Editorial
Team on 21 April 2006
New 2-sulfonyl-2-hetaryl-ethylamines
from Otava
High reactivity of aliphatic primary amino-group 2-sulfonyl-2-hetarylethylamine gives easy reaction with carboxylic acids chloroanhydrides and imidazolides, sulfonyl chlorides, active halogen compound
2-Arylethylamines is a wide valuable family of biologically active compounds Recently Otava has developed the synthesis of novel 2-arylsylfonyl-2-hetarylethylamines
This article was originally published on Laboratorytalk on 15 Nov 2005 at 8.00am (UK)
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The library was generated using receptor-based virtual screening of the Otava's drug-like Green Collection
This class of compounds is not referenced in literature.
It has synthesized chemicals with 3-pyridyl-, 2-furyl-, 2-thienyl- as Het-moiety and with 2-thienyl-, phenyl-, p-tolyl-, 4-fluorophenyl-, 4-chlorophenyl-, 4-methoxyphenyl-, etc as R-group.
On request compounds with any other groups Het- and R- may be synthesized within 1-2 months.
The virtual database of 2-sulfonyl-2-hetarylethylamine building blocks can be downlonded.
Due to high reactivity of aliphatic primary amino-group 2-sulfonyl-2-hetarylethylamine easily reacts with carboxylic acids chloroanhydrides and imidazolides, sulfonyl chlorides, active halogen compounds and other electrophylic reagents.
Most of the reaction products are simply purifying crystalline substances.
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