Product category:
Assay kits
News Release from: Perceptive Instruments | Subject: Comet Assay IV
Edited by the Laboratorytalk Editorial
Team on 14 December 2007
Comet Assay used in biomonitoring for
DNA damage
CSAO began using the Comet Assay in 2005 primarily to assess the genotoxic potential of chemicals such as formaldehyde to which pathology and anatomy staff are exposed
Perceptive Instruments have a new case study on the use of Comet Assay IV, contributed by the Centre of Occupational and Environmental Health (CSAO), an operative unit of the Portuguese National Institute of Health (Insa) The CSAO's primary function is to study the health impact of environmental factors, mainly in occupational environments
This article was originally published on Laboratorytalk on 7 Feb 2005 at 8.00am (UK)
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Score with a single click on a comet
Fourth generation interactive video-based analysis system for scoring cells using the single cell gel electrophoresis technique introduces one-click scoring
The comet assay is widely used as a biomonitoring tool for DNA damage due to its versatility and relative simplicity.
Due to it's extreme sensitivity the comet assay detects DNA damage at very low exposure levels.
These characteristics make the assay suitable for analysing cells such as leucocytes, exfoliated bladder cells, nasal and buccal epithelial cells leading to improved assessment of human exposure.
The group chose Comet Assay IV to score slides because of it's ability to provide rapid scoring using one-click capture and analysis, automatic computation of the main parameters and storage of images and data.
Statistical analysis of data is performed with the spreadsheet generator Excel macro supplied with Comet Assay IV.
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