Product category:
Clinical chemistry analysis
News Release from: Randox Laboratories | Subject: Cytokine and Growth Factor Assays
Edited by the Laboratorytalk Editorial
Team on 30 April 2008
High sensitivity, multi-analyte cytokine
assays
The Randox High Sensitivity Cytokine and Growth Factor Assays provide this sensitivity, using a combination of highly specific antibodies and advanced chemistries.
Cytokines and growth factors circulate in low quantities, thus high sensitivity detection is essential The biochip assay uses a 9mm activated biochip with spatially discrete test regions containing antibodies specific to each of the analytes
This article was originally published on Laboratorytalk on 12 Aug 2005 at 8.00am (UK)
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This multi-analyte approach enables up to 12 cytokines and growth factors to be detected simultaneously in a single, 100ul serum sample, providing valuable information relating to each cytokine under test and associations between cytokines.
Cytokines are soluble signalling proteins and glycoproteins employed in cellular communication during immune and inflammatory responses.
They have also been implicated in other pathological conditions, such as cancer and cardiovascular diseases.
Cytokines can affect their host cell (autocrine), nearby cells (paracrine) or in some cases, distant cells (endocrine).
They are characterised by considerable redundancy, so measuring a single cytokine may miss an important facet of a response progression.
In addition, the common cascading of cytokines can more readily be observed if a suite of these proteins is measured simultaneously, leading to a greater understanding of the disease process and subsequent management; this has become increasingly desirable in laboratory medicine.
Quality control is an important aspect in all multiplex assays; Randox offer a High Sensitivity Quality Control Assay to complement this assay.
With a rapidly increasing portfolio of multiplex assays, covering a broad range of analytes, Randox will have a test panel to suit your needs. Request a free brochure from Randox Laboratories ...
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