Product category:
Mass spectrometers
News Release from: Shimadzu Scientific Instruments | Subject: LCMS-IT-Tof
Edited by the Laboratorytalk Editorial
Team on 27 October 2005
Hybrid mass spectrometer secures R and D
100 award
The new hybrid ion trap-time-of-flight instrument was selected as being a breakthrough technology and achieved the award in the analytical instruments category
Shimadzu Scientific Instruments reports that its new mass spectrometer has received an R and D Magazine 2005 R and D 100 award Shimadzu's liquid chromatography mass spectrometry ion trap time-of-flight (LCMS-IT-Tof) is designed for a wide range of uses including biomarker studies, metabolomics, proteomics, metabolite identification, environmental analyses, forensics use, and homeland security functions
This article was originally published on Laboratorytalk on 14 Apr 2005 at 8.00am (UK)
Related stories
First LCMS-IT-Tof mass spectrometer
Novel hybrid liquid chromatograph/mass spectrometer is intended for biomarker discovery, metabolite identification, and proteomics research
Analysis of Amoxicillin using LCMS
Shimadzu Scientific Instruments has published the application note, Analysis of Amoxicillin using the LCMS-2010EV and the LCMS-IT-Tof
Developed by a research team of scientists and engineers at Shimadzu, the LCMS-IT-Tof instrument enables researchers to perform multiple levels of ion fragmentation with high mass accuracy.
Specifically, the LCMS-IT-Tof - with more than a dozen issued and pending product technology patents - was designed to deal with the stringent requirements of identification of pharmaceutical impurities, natural products and metabolites.
Obtaining exact mass measurements with high sensitivity and with multiple levels of fragmentation is critical to taking the guesswork out of compound identification and speeding up analytical processes.
Further reading
Formula Predictor LCMS system identifies unknowns
Answering researchers' need for improved accuracy and speed in identification of unknown components, Shimadzu has developed a new system featuring its award-winning LCMS-IT-Tof mass spectrometer
LCMS-IT-Tof analyses polyphenols in green tea
This application note introduces the analysis of green tea extract, utilising the LCMS-IT-TOF, which couples atmospheric pressure ionisation with ion-trap (IT) and time-of-flight (Tof) technologies
"This is the first ion trap-time-of-flight instrument for HPLC use that's widely available to researchers," noted Shigehiko Hattori, president and CEO of Shimadzu.
"We worked very hard to combine the best benefits of ion traps and time-of-flight mass spectrometers, and to have our rigorous research and development garner such a prestigious award is a real signal that our efforts were successful".
The Shimadzu LCMS-IT-Tof maintains its high sensitivity by significantly improving control over the entire ion collection and ion transfer process.
Major innovations in the design include improvements to collect more ions, compress ions more rapidly into the trap with high efficiency, and the efficient transfer of ions to the Tof (time-of-flight) portion of the instrument.
Coupling atmospheric pressure ionisation with its IT (ion trap) and Tof technologies, the LCMS-IT-Tof delivers both high mass accuracy, and high mass resolution (>10,000 at 1000m/z), says Shimadzu.
It is designed to maximise sensitivity and selectivity, and redefines the capabilities of the quadruple ion trap - which not only supports high precursor ion selection and fragmentation of ions before ejection into the Tof, but also allows ballistic ion ejection into the Tof to minimise energy spread of ions exiting the trap.
In March 2005, the LCMS-IT-Tof also won the Silver Award for best new product at the Pittsburgh Conference (Pittcon). Request a free brochure from Shimadzu Scientific Instruments ...
• Shimadzu Scientific Instruments: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page
Search the Pro-Talk network of sites
