Product category:
Chromatography software
News Release from: Shimadzu Scientific Instruments | Subject: Real time in-situ monitoring of organic reactions
Edited by the Laboratorytalk Editorial
Team on 05 January 2006
Monitor organic reactions using FTIR
fibre optics
Shimadzu Scientific Instruments has published the application note, 'Real time in-situ monitoring of organic reactions using an FTIR fiber optic system'
The formations of intermediates in chemical reactions play integral roles in the final result of the chemical reaction Often, these intermediates cannot be monitored in real time and even in cases where it is possible to trap or isolate the intermediate, its characterisation and determination of purity and yield can consume many hours
This article was originally published on Laboratorytalk on 21 Mar 2003 at 8.00am (UK)
Related stories
Chromatography data to 21 CFR Part 11
Latest version of client/server chromatography data system aimed at the pharmaceutical sector has new inbuilt features to ensure compliance with electronic signatures regulation
The use of the FTIR as a reaction monitor can aid in recognising formation of intermediates as well as in determining depletion of reactants and formation of products.
In most cases, it is not feasible to remove aliquots of a reaction mixture for measurement with traditional IR accessories such as liquid cells.
The use of a fibre optic probe system allows real-time monitoring of the reaction in the reaction vessel.
In this communication, a system is described that allows real-time monitoring of chemical reactions at elevated or sub ambient temperatures without jeopardising the reaction system.
It shows that FTIR is a viable way of monitoring an organic reaction in real-time where there are discernable differences in functional groups between reactants and the products.
The use of a fibre optic probe can enhance this capability by enabling monitoring of the reaction in-situ. Request a free brochure from Shimadzu Scientific Instruments ...
• Shimadzu Scientific Instruments: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page
Search the Pro-Talk network of sites
