Product category:
Chromatography accessories
News Release from: Shimadzu Scientific Instruments | Subject: SIL-20A
Edited by the Laboratorytalk Editorial
Team on 24 February 2006
Autosampler decreases
cross-contamination
The SIL-20A is a no sample loss autosampler with needle-in-the-flow-path design and an adjustable needle stroke that ensures researchers get the sample injection they need without wasting sample.
Shimadzu Scientific Instruments (SSI) announces the launch of its new SIL-20A autosampler Delivering excellent analysis efficiency, the SIL-20A features improvements in sample injection speed, accuracy, and processing capacity
This article was originally published on Laboratorytalk on 17 Nov 2005 at 8.00am (UK)
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SSI's new autosampler - designed to perform analyses faster and better without carryover - employs new cross-contamination countermeasures to maintain sample purity, even with high-sensitivity LC-MS/MS detection.
The SIL-20A's newly designed injection port and needle tip reduce carryover and trapped sample, resulting in exceptional carryover performance.
From the proprietary coating on the external surface of the needle to the high-pressure valve rotor material, choices were made to eliminate carryover.
Further reading
High performance, high sensitivity LCMS
Incorporates a new drying gas system that creates a finer spray mist to permit highly sensitive analysis, particularly for low to medium polarity compounds
High sensitivity high performance FTIR
Features a highly optimised, high energy throughput optical system that results in a signal to noise ratio of 40,000:1
Additionally, the needle seal/injection port is mounted directly on the valve, eliminating the need for a sample transfer line and reducing possible carryover arising from unswept areas in tubing connections.
SSI also offers alternative needle and rotor materials for those compounds that may have an affinity for any of the standard materials.
"Carryover reduction has become one of the key design elements for autosamplers due to the increased sensitivity of HPLC detectors, especially LC-MS/MS," notes Curtis Campbell, Shimadzu Scientific Instruments' HPLC product manager.
"Studies with chlorhexidine, a known troublesome, very basic antibiotic compound, have shown the SIL-20 to be more than 100 times better than other commonly available commercial autosamplers under similar conditions".
The SIL-20A is not only more accurate than traditional autosamplers, but is also the world's fastest at less than ten seconds for a 10ul injection.
Fully optimised, the time between injections can be less than five seconds - perfect for flow injection MS analysis.
Naturally, with increased speed comes the need for increased capacity, and the SIL-20A can accommodate 175 vials (8X40 mm, 1ml) or two microtiter plates.
The addition of a rack changer means that up to 12 standard or deep-well microtiter plates (96 or 384 well format) can be accommodated.
The SIL-20A is a no sample loss autosampler with needle-in-the-flow-path design and an adjustable needle stroke that ensures researchers get the sample injection they need without wasting sample.
The SIL-20A's metering pump is driven by a 3nl/step resolution motor drive, providing excellent durability and injection volume accuracy. Request a free brochure from Shimadzu Scientific Instruments ...
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