Product category:
Culture media
News Release from: Sigma-Aldrich | Subject: Stemline
Edited by the Laboratorytalk Editorial
Team on 24 June 2005
Expansion medium is optimised for human
T cells
Culture medium offers a consistently high T cell yield in a serum-free environment, while the elimination of fetal bovine serum effectively reduces performance variability and removes safety risks
Sigma has introduced Stemline T cell expansion medium, a new serum-free T cell medium optimised specifically for expansion and activation of human T cells After a direct comparison to a commercially available competitor's serum free media, Stemline T Cell expansion medium has been selected as the best medium for T cell expansion in an upcoming clinical trial supported by Gerhard Bauer of the Siteman Cancer Center GMP facility at Washington University in St Louis, USA
This article was originally published on Laboratorytalk on 19 Oct 2006 at 8.00am (UK)
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This new culture medium offers a consistently high T cell yield in a serum-free environment, says Sigma.
The elimination of fetal bovine serum effectively reduces performance variability and removes safety risks associated with possible adventitious agents in serum.
T cells expanded ex vivo in Stemline T Cell expansion medium exhibit rigorous and consistent growth kinetics, maintenance of the proper CD4/CD8 ratio, and both ex vivo (chromium release assay) and in vivo functionality (graft vs host induction in NOD/SCID- and mice).
"We're very excited about the release of the new member of the Stemline media platform," commented Lisa Masterson, cell culture product manager at Sigma-Aldrich.
"It has shown very promising results in bench scale experiments and I look forward to the results from the upcoming clinical studies.".
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