Protocol system speeds vaccine manufacturing

Synbiosis has announced that its Protocol automatic zone measuring system has features designed to improve the speed of analysing SRD plates, ensuring flu vaccines can be manufactured more rapidly.

The Protocol can generate results from a 16-zone SRD (single radial immunodiffusion) plate of flu vaccines in minutes.

This means scientists can analyse 10 SRD plates in the time it would take to manually analyse one.

The system's software supports 21CFR Part 11 and includes a gantry control, allowing automatic imaging of larger SRD plates when required.

These features make Protocol suitable for increasing productivity in any GMP vaccine production facility.

Protocol's computer-controlled, high-resolution CCD camera captures precise zone images and its software automatically assesses not just two points from around the circular zone, as would be performed manually, but simultaneously analyses multiple points.

The software then calculates a precise average diameter measurement to provide an accurate indication of vaccine potency.

The reproducible results are automatically transferred into Microsoft Excel or to a Lims system for storage or statistical analysis where a vaccine's batch number or name can be entered into the Protocol software.

An image library is also created alongside, permitting staff to see an SRD plate if there is a query after it is disposed of.

These files are designed to simplify the production of raw data and professional reports for each flu vaccine.

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