Product category:
Nucleic acid sequencing and synthesis
News Release from: Syngene | Subject: Dyversity
Edited by the Laboratorytalk Editorial
Team on 14 December 2007
2D gel image analyser used at Imperial
College
Scientists in the Institute of Biomedical Engineering at Imperial College are using Dyversity to rapidly image 2D DIGE (differential gel electrophoresis) gels containing Cy dye labelled proteins
Syngene reports that one of the UK's top universities, Imperial College London, is using Dyversity, its 2D gel imaging system, to assist in precise identification of proteins associated with directing embryonic stem cells (ESCs) to a particular cell lineage The proteins were isolated from two different conditioned media, where both media direct murine ESCs to differentiate into mesoderm lineages
This article was originally published on Laboratorytalk on 16 Feb 2006 at 8.00am (UK)
Related stories
CCD is alternative to laser scanner for 2D gels
Syngene announces the availability of Dyversity, its new automated imager, designed to save time with producing precise images of 2D protein gels
CCD is ten times faster than laser for 2D gel
Syngene reports a new study which demonstrates that Dyversity, its automated 2D gel imager, can capture high quality 2D protein gel images significantly faster than the leading laser scanner
Therefore, by identifying and analysing any common proteins seen on the Dyversity images, researchers at the Institute of Biomedical Engineering in collaboration with the stem cell bio-processing group in the department of chemical engineering, hope to determine which signalling factors direct differentiation.
Judit Nagy, director of proteomics facility, Institute of Biomedical Engineering, commented: "Due to the potential for ESCs to develop into any cell line, they could become a good source of bone tissue, for example.
"However, before we can use ESC in this way, we have to find out which proteins direct differentiation and this is where we hope our proteomics approach using 2D DIGE gels and Maldi-tof analysis will provide some clues.
"We use Dyversity as part of this work because it is capable of generating high resolution images of our 2D DIGE gels in a few minutes, which is very important when we compare different gels to locate common proteins," concluded Nagy.
Laura Sullivan, Syngene's divisional manager stated: "We are delighted to see our Dyversity system being used as part of critical stem cell research at such a prestigious university like Imperial College. Request a free brochure from Syngene ...
"Their application shows that Dyversity is a high performance system capable of imaging very complex 2D protein gels and should be seen as an invaluable tool for any proteomics research programmes.".
• Syngene: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page
Search the Pro-Talk network of sites
