LC-MS/MS solution helps FDA keep pet food safe
A
Thermo Fisher Scientific (Chromatography) product story
Edited by the Laboratorytalk editorial team
Aug 8, 2007
Thermo Fisher Scientific has announced that a new method to detect melamine content in catfish has been developed by the US Food and Drug Administration (FDA)
The detection method was developed following the recent discovery of contamination from imported food sources.
The method uses Thermo Scientific instrumentation for a liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) solution, and is published in the US FDA's Laboratory Information Bulletin No 4396, 'Determination of Melamine Residues in Catfish Tissue by Triple Quadrupole LC-MS/MS with HILIC Chromatography'.
Recent news coverage about the presence of melamine - an industrial chemical used in the manufacturing of plastics, flame retardants and other products - in pet food, animal feed, wheat gluten and other protein-based food commodities has raised the general public's concern about the chemical in the food supply chain for both animals and humans.
According to the bulletin, "because animals may eat food contaminated with melamine residues, there is a need for analytical methods to determine melamine residues that may be present in animal tissues".
The FDA performed the LC-MS/MS method using the Thermo Scientific TSQ Quantum triple quadrupole mass spectrometer coupled to a Thermo Scientific Surveyor MS pump and autosampler.
Additionally, Thermo Scientific Xcalibur data system software was used to acquire and analyse the data.
The FDA's method showed that the Thermo Scientific instrumentation detected melamine at levels of 10 parts per billion in catfish extract, thereby exceeding the agency's requirements.
Melamine is not approved for use in food or animal feed.
Contaminated vegetable proteins imported into the United States from China were found to be used as ingredients in pet food, which sparked a nationwide pet food recall that began March 15, 2007.
Additionally, a portion of the tainted pet food was used to produce farm animal feed and fish feed.
The FDA and the US Department of Agriculture discovered that some animals that ate the tainted feed had been processed into human food.
The Thermo Scientific TSQ Quantum triple quadrupole system is the only instrument that enables Highly Selective Reaction Monitoring (H-SRM), which facilitates the quick and efficient analysis of complex samples such as animal tissue.
The Thermo Scientific LC-MS/MS solution yielded accuracy and precision values for this method that were well within the guidelines of the FDA for analytical method development and validation.
Not what you're looking for? Search the site.
Google Ads
Contact Thermo Fisher Scientific (Chromatography)
Related Stories
- UV/visible spectrophotometers on the seven seas
- Jeol JSM-7600F e-beam SEM advances nanoscience
- Hach Lange analyser boosts efficiency at NLS lab
- Microchannel plate banks used in space research
- SGL Group expands testing using Zwick equipment
Articles by product category
-
Analytical instruments (8,805)
- Analytical instruments (13)
- Chemical analysis equipment (631)
- Chromatographs: gas (241)
- Chromatographs: liquid, ion, gel, HPLC (427)
- Chromatography accessories (503)
- Gas analysis equipment (219)
- pH and conductivity meters (114)
- Cameras and imaging systems (820)
- Electron microscopy systems (209)
- Optical microscopes (448)
- Microscope supplies and accessories (558)
- Mass spectrometers (458)
- Spectroscopy (535)
- Other analytical instruments (592)
- Particle size analysis equipment (555)
- Microplate readers (39)
- Temperature, pressure and flow measurement (262)
- Spectrophotometers (273)
- Titration equipment (655)
- Ultrasound equipment and ultrasonic spectroscopy (118)
- Viscometers and rheometers (346)
- Oscilloscopes (83)
- Mechanical testing equipment (492)
- Test and calibration instrumentation (214)
-
Life sciences and clinical laboratory equipment (3,579)
- Life sciences and clinical laboratory equipment (3)
- Clinical chemistry analysis (898)
- Nucleic acid sequencing and synthesis (637)
- Genomics (459)
- Proteomics (450)
- Assay kits (185)
- Microbiology (383)
- Polymerase chain reaction (PCR) (240)
- Cell/tissue handling and counting (324)
-
Computer hardware (826)
- Computer hardware (7)
- Dataloggers (302)
- I/O devices (362)
- Monitors and peripherals (50)
- Process control and networking (79)
- PLCs (26)
-
Industry news (19)
- Industry news (19)
-
Laboratory equipment and wares (5,937)
- Laboratory equipment and wares (5)
- Safety and ventilation equipment (322)
- General lab equipment (831)
- Workstations (61)
- Detectors, sensors and probes (375)
- Lab automation equipment and robotics (651)
- Laboratory furniture and storage (151)
- Gas handling (125)
- Heating: ovens, furnaces, autoclaves (331)
- Fermentation and incubation equipment (73)
- Microplates/microarrays and readers (397)
- Microfluidics/Lab-on-a-chip systems (142)
- Distillation equipment (16)
- Sampling equipment (156)
- Environmental chambers (88)
- Fume cupboards ductless (79)
- Laboratory glassware (400)
- Liquid handling (415)
- Cooling: refrigeration (198)
- Washing and sterilisation equipment (207)
- Fume cupboards ducted (31)
- HTS and combinatorial chemistry equipment (57)
- Evaporation equipment (166)
- Weighing and balancing (240)
- Centrifuges (47)
- Water purification (213)
- Laboratory plasticware (160)
-
Laboratory supplies and consumables (1,271)
- Laboratory supplies and consumables (2)
- Culture media (119)
- Reagents and catalysts (169)
- Antibodies (203)
- Cleaning products (65)
- Reference standards (178)
- Chemicals and biochemicals (534)
-
Pumps, Valves, Filters (708)
- Automated Valves (66)
- Filtration equipment and supplies (176)
- Metering pumps (109)
- Other pumps (63)
- Peristaltic pumps (65)
- Vacuum pumps and compressors (144)
- Manual Valves (85)
-
Services (2,989)
- Contract research (889)
- Laboratory and scientific exhibitions and conferences (230)
- Laboratory and scientific recruitment (26)
- Laboratory and scientific consultancy services (288)
- Laboratory and scientific training and education (413)
- Laboratory building and design (50)
- Laboratory and scientific manufacturing services (136)
- Laboratory and scientific professional organisations (482)
- Laboratory and scientific books and publishing (475)
-
Computer software (2,882)
- Computer software (4)
- Chemical modelling software (181)
- Laboratory and scientific databases (327)
- Instrument control software (320)
- Laboratory information management system (LIMS) (721)
- Mathematical software (163)
- Process control and networking software (52)
- Data acquisition software (171)
- Chromatography software (284)
- Spectroscopy software (92)
- Analytical, statistical and report generating software (284)
- Data management software (283)
