Product category:
Spectroscopy software
News Release from: Theoprax-research | Subject: Theoprax method
Edited by the Laboratorytalk Editorial
Team on 03 December 2001
Optimising pH to optimise reactions
The pH value of the solution is an essential parameter of a reaction, and the right pH value is vital for a high yield, says Theoprax Research
A pH spectrum helps you to find out the right pH-value for your reaction So far you have been able to record IR spectra, NMR spectra, UV spectra, and so on
This article was originally published on Laboratorytalk on 28 Jun 2004 at 8.00am (UK)
Related stories
Generic methods for HTP
ACD/Labs and Supelco join forces to design generic chromatographic methods for the walk-up and high-throughput laboratory
No worries over VXI obsolescence
VXI Tektronix has made its product line obsolete, potentially creating a major headache for users. A solution may be in a new replacement programme just announced for the UK from TTi
Now with Theoprax software you can record pH spectra to study the interaction between different molecules in dependence on the degree of dissociation of their functional groups.
With the help of the Theoprax measuring method, you are able to record pH-spectra, which show among other things the interaction between two differently loaded molecules in dependence on the pH-value.
The Theoprax method, a new way to use conductivity measurement in analytical chemistry, opens up new prospects in complex chemistry, pharmaceutical chemistry and biochemistry.
In complex chemistry, the pH spectrum makes it possible to make a statement about the concentration of the complex, complexing agent, and central ion.
Also you can make a statement about the stoichiometry of the complex in solution.
The pH spectrum shows you how the stoichiometry of the complex changes with the pH value of your solution.
Furthermore, it shows the preference of the complexing agent/central ion for an metal ion/complexing agent in the presence of other metal ions/complexing agents.
The pH spectrum also shows the optimum pH value for complex formation.
In pharmaceutical chemistry and biochemistry for example you can use the Theoprax method as a diagnostic tool to speed up your separation technique (affinity chromatography).
The pH spectrum makes it possible to show the enzyme inhibitor complex, enzyme substrate complex, the catabolism of the substrate as well as the pH activity curve of the enzyme.
It is also possible to show the interaction between antigen and antibody.
• Theoprax-research: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page
Search the Pro-Talk network of sites
