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Product category: Instrument control software
News Release from: Thermo Fisher Scientific Laboratory Equipment | Subject: MCA
Edited by the Laboratorytalk Editorial Team on 05 December 2002

Melting curve analysis system

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Software suite has been designed for ease of use, logging data and producing easy to read differential melting curve peaks that are then autoscored and designated

Thermo Hybaid announces the launch of a flexible new system for melting curve analysis The MCA system is based on the proven technology employed in Thermo Hybaid's Dash instrument, which primarily addressed the genotyping market using either the Dash or McSNP methodologies

The new MCA system has significantly enhanced functionality to address the breadth of requirements of the many techniques utilising melting curve analysis.

New embedded and front-end software will allow researchers to design a protocol within the temperature range of 20-100C.

Up to eight excitation and eight emission filters can be chosen per 96 well plate reading, allowing the usage of a number of different fluorescent systems.

The system's powerful software suite has been designed for ease of use, logging all data from the MCA system and producing easy to read differential melting curve peaks that are then autoscored and designated.

This data can additionally be viewed in a number of different aspects and is easily exported to other Windows-based programs for further manipulation and presentation.

Melting curve analysis is proving to be the method of choice for a number of diverse techniques from mutation detection, post-PCR analysis and DNA methylation profiling though to SNP scoring and detection by heteroduplex analysis.

The MCA system is designed with the flexibility to cater for all these techniques and to perform the analysis with ease, speed and efficiency.

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