Product category:
Mass spectrometers
News Release from: Thermo Fisher Scientific (Mass Spectrometry) | Subject: LTQ Orbitrap
Edited by the Laboratorytalk Editorial
Team on 15 February 2006
Proteomics improve quantitation,
characterisation
Proteomics suite is designed to leverage the unmatched performance, speed, sensitivity and accuracy of market-leading ion trap mass spectrometers for definitive quantitation of protein mixtures
Thermo Electron unveils several new additions to its proteomics suite These include its novel LTQ Orbitrap hybrid mass spectrometer, new techniques for peptide fragmentation and software for data interpretation, all which dramatically enhance and expand the potential for protein identification and quantification
This article was originally published on Laboratorytalk on 10 Jun 2005 at 8.00am (UK)
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Thermo says its Proteomics suite is designed to leverage the unmatched performance, speed, sensitivity and accuracy of its market-leading ion trap mass spectrometers for definitive quantitation of protein mixtures.
Some of these new solutions include the LTQ Orbitrap, the first commercial mass analyser based on an entirely new detection principle to be introduced to the market in over 20 years.
This hybrid instrument greatly improves protein characterisation, accelerates protein database searches and reduces false identification rates, it says.
Thermo has also introduced several new approaches to protein quantitation, such as Pulsed-Q Dissociation (PQD), a new fragmentation technique that eliminates the low mass cut-off for ion traps and allows quantitation with iTRAQ labeling reagents.
iTraq is a stable isotope method for relative protein quantitation using mass spectrometry.
In addition, BioWorks software has been extended to facilitate the use of all major protein quantitation techniques, namely Silac (stable isotope labeling with amino acids in cell culture), metabolic labelling, iTraq and Icat (isotope coding affinity tagging).
As a result, Sequest protein identifications can now easily be combined with quantitative data for an accurate view of protein expression levels.
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