Product category:
Mass spectrometers
News Release from: Thermo Fisher Scientific (Mass Spectrometry) | Subject: QuickQuan 2.0
Edited by the Laboratorytalk Editorial
Team on 02 April 2007
Alleviating bottlenecks in sample
analysis
Recently showcased at Pittcon 2007, Thermo Scientific QuickQuan 2.0 for automating high-throughput LC-MS/MS assays, designed to alleviate the bottleneck of sample analysis in early drug discovery
QuickQuan delivers rapid LC-MS/MS optimisation through an automated on-line infusion mode and valve switching design, allowing precise auto-tuning with high sensitivity and maximising successful automated quantification of chemically diverse compounds All analytical information can be stored in Microsoft Access or Oracle databases, which facilitates rapid data exchange across global networks
This article was originally published on Laboratorytalk on 13 Nov 2003 at 8.00am (UK)
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QuickQuan 2.0 incorporates new features which further extend the capabilities of the software to non-GLP (good laboratory practice) laboratories performing medium to high throughput quantitation assays.
The unique Autosampler Infusion feature introduced in this version enables automated compound optimisation.
When coupled with a CTC HTS or HTC PAL autosampler, the autosampler can be configured for use as an infusion pump, providing more accurate optimisation results than traditional techniques at a rate of approximately 70 seconds per compound.
Automated optimisation of MS/MS parameters enables users to optimize hundreds of compounds without manual intervention.
In addition QuickQuan 2.0 has the ability to store results for method generation in a Microsoft Access or Oracle database, removing the need for redundant optimisation when reanalysing samples or transferring instrument methods.
When networked with any of the Thermo Scientific TSQ Quantum triple quadrupole mass spectrometers, the system can access this database and perform sample analysis without requiring reoptimisation on each individual instrument.
In addition, QuickQuan 2.0 is available as a pre-packaged hardware solution that enables column switching without guess work or plumbing.
With this solution, users are able to proceed from optimisation to sample acquisition without interruptions.
QuickQuan 2.0 includes templates for the automated generation of both instrument and processing methods, thereby eliminating the need to create methods manually when studying a large number of compounds.
The software also allows users to automatically generate customizable Excel summaries and Xreports, minimising time required for data processing and review.
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