Product category:
Assay kits
News Release from: Trevigen | Subject: HT Parp/apoptosis assay
Edited by the Laboratorytalk Editorial
Team on 25 February 2008
High-throughput assays for
Parp/apoptosis
The HT Parp/apoptosis assay is an Elisa which semi-quantitatively detects PAR deposited onto immobilised histone proteins (via Parp activity) in a 96-well format
Trevigen launches high-throughput Parp/apoptosis assays ideal for measuring the activity of Parp in 96-well plates Cell extracts can be obtained using our newly-developed, higher-throughput procedure before, during and after apoptosis induction
During apoptosis, Parp-1 which catalyses the NAD dependent addition of poly (ADP-ribose) (PAR) onto various cytoplasmic and nuclear proteins, is cleaved from its enzymatically active form (about 116kDa), to its inactive form (85kDa).
Trevigen offers two formats of the HT Parp/apoptosis assay: Cat 4684-096-K (colorimetric) and Cat 4685-096-K (chemiluminescent).
Additional histone-coated strip wells (Cat 4677-096-P) are available separately.
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