Product category:
Chemicals and biochemicals
News Release from: Trevigen | Subject: 3D cell proliferation kits
Edited by the Laboratorytalk Editorial
Team on 14 May 2008
Four new assay kits for 3D cell
proliferation
Trevigen has introduced four new 3D cell proliferation kits including a core kit and three different kits containing basement membrane extract, laminin I, and collagen I
In 3D Culture, cells are grown in a microenvironment of specialised proteins which mimics in vivo conditions and allows the cells to organise into complex structures rather than uniform monolayers Various types of cells require different specialised proteins for optimal growth conditions and these extracellular matrices can play an important role in modulating cellular response to pharmacological compounds
This article was originally published on Laboratorytalk on 31 Jan 2006 at 8.00am (UK)
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For these reasons, conversion to 3D culture with different matrices is highly desirable, but until now there has not been a practical way to evaluate cell proliferation from 3D cultures.
These are the first standardised kits engineered for assessing the effects of compounds or genetic alteration on cell proliferation in 3D culture.
The high throughput 96 stripwell formats allow one step quantitative analysis and colorimetric detection.
Protocols are provided for tumourgenicity and cytotoxicity.
Trevigen is a rapidly growing biotechnology company focused on the development of products and technology for cancer research, emphasizing apoptosis, DNA damage and repair, and cancer cell function and behaviour.
Trevigen has been a long-standing provider of quality reagents and kits for researchers investigating programmed cell death and DNA damage and repair.
A logical extension of the focus on cancer research has been the recent development of assays for cancer cell function and behaviour including angiogenesis, cell invasion and tumour formation.
Currently, the product portfolio contains over 500 products categorised into four processes - apoptosis, DNA damage and repair, angiogenesis, and oxidative stress.
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