HTP for nanolitre pipetting system

High throughput option for liquid handling system enhances capacity for compound dissolution applications such as compound-to-assay plate creation

TTP LabTech has launched a high throughput option for its Mosquito nanolitre liquid handling system, further enhancing its capacity for compound dissolution applications such as compound-to-assay plate creation using a single step dilution.

Mosquito can pipette accurately and reproducibly throughout the 50nl-1.2µl volumetric range producing CVs of <10% at 50nl.

TTP says this, along with its innovative reel of 35,000 micropipettes, has revolutionised ultra-low-volume liquid handling possibilities.

The disposable tips eliminate cross-contamination worries, and working at such small volumes helps to reduce assay costs significantly.

Mosquito HT, the new high throughput option, offers vastly increased walk-away time, making it ideal for sub-cloning plates during compound dissolution in 96, 384 and 1536 plates.

The extended walk-away time is created by the combination of a new deck variant with five SBS plate positions (increased from the standard two-position deck) together with a robotic plate handler and integrated software.

The five-position Mosquito HT can make four copies of a 384 plate in under five minutes, or pool four x 384 plates into a 1536 plate in under 12 minutes.

A Hamilton Swap robotic arm manipulates plates to and from the work surface, allowing Mosquito to run plate-to-plate transfers without intervention for up to 200 plates.

Mosquito's volumetric performance remains excellent throughout.

Visual Basic compatible software provides a standard automation interface to third-party devices, so Mosquito HT can integrate seamlessly with existing instrumentation to simplify and improve the compound dissolution process.

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