Product category:
Viscometers and rheometers
News Release from: Viscotek Europe | Subject: Lals
Edited by the Laboratorytalk Editorial
Team on 27 January 2005
Unlocking the secrets of large
biomolecules
Technical data demonstrate the utility of low angle light scattering (Lals) detector in directly measuring the molecular weight of large molecules such as polysaccharides
Unlike multi-angle light scattering techniques that can only determine molecular weight by extrapolation, the Lals technique measures molecular weight directly and thus is inherently more accurate, says Viscotek Europe Consequently the technique is of considerable importance to scientists looking to make routine direct determination of absolute molecular weights of large biomolecules and polymers
This article was originally published on Laboratorytalk on 22 Jul 2008 at 8.00am (UK)
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Absolute molecular weights without extrapolation
Viscotek has announced new technical data that demonstrates how its unique low angle light scattering (Lals) detector achieves results not possible using traditional light scattering technologies.
Viscotek's Lals is available as a complete multi-detector (Lals/ viscometer/ UV/RI) system or as a stand-alone detector that can be coupled to any GPC/SEC system to obtain absolute molecular weights directly.
The Lals detector measures scattered light at 7deg, close enough to zero that the measurement is direct with no need to extrapolate or calculate as in all other GPC-light scattering techniques.
This is extremely important when studying large biomolecules such as polysaccharides, where the traditional extrapolation using other light scattering instruments gives large data errors.
A technical paper is available providing an unbiased introduction to the theory of light scattering detection and why low angle light scattering measurement is important.
The paper is precisely illustrated with examples and proved with mathematical theory.
Application papers are also available. Request a free brochure from Viscotek Europe ...
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