Product category:
Laboratory and scientific databases
News Release from: Waters | Subject: MarkerLynx DB
Edited by the Laboratorytalk Editorial
Team on 04 July 2005
Accelerate metabonomics biomarker
discovery
Database application allows scientists to process LC/MS and GC/MS data and perform 3D peak integration, noise elimination, metabolite removal, peak alignment and multivariate statistical analysis
LC/MS and GC/MS-driven biomarker discovery holds a key to understanding mechanisms of toxicity for the development of new medicines, and the optimisation of industrial and agrochemical processes In pursuit of metabonomics biomarker knowledge, these information-rich techniques require sophisticated software tools to process and interpret large amounts of data
This article was originally published on Laboratorytalk on 2 Aug 2004 at 8.00am (UK)
Related stories
Enabling technology for E-lab notebook
Diosynth selects Waters NuGenesis Scientific data management solution for its internal E-lab notebook initiative
Apotex selects scientific data management system
Company plans to reduce cycle time in new product development by standardising on data management platform, which will be deployed at up to 15 sites worldwide
In response to this challenge, Waters has announced the introduction of the dedicated MarkerLynx DB (database) application manager for MassLynx 4.1 software for multivariate statistical analysis and database searching.
Building upon the success of the MarkerLynx application manager introduced in 2003, MarkerLynx DB features improved peak detection, enhanced statistical tools, and new dynamic database searching and storage capabilities for the identification of important biomarkers, launched directly from the statistical results browser.
According to Brian Smith, senior director, pharmaceutical business development: "With the introduction of MarkerLynx DB, Waters sets a new standard in metabonomics and biomarker data management.
Further reading
Taking liquid chromatography a stage further
Claiming to be the first end-to-end ultra performance liquid chromatography system offering specially designed column chemistries, hardware, software, and documentation
Expanded chromatography control with this software
Acquires data and controls the operation of and processes data from Waters brand instrumentation as well as Agilent photodiode array detectors, liquid chromatographs, and gas chromatographs
"We have listened to the needs of our customers and collaborators, and have delivered the best in data analysis, interpretation and archival tools for a truly comprehensive solution".
Metabonomics helps predict the efficacy and toxicity of new drug compounds and has the potential to impact characterisation and efficiency of industrial operations, says Waters.
To achieve success in metabonomics, scientists must develop reliable and efficient assays to rapidly detect as many analytes as possible with a high degree of sensitivity and resolution.
The next crucial step is to process and interpret large amounts of information-rich data to derive meaningful results.
With the MarkerLynx DB application manager, the company says scientists can seamlessly process LC/MS and GC/MS data and perform such tasks as three-dimensional peak integration, noise elimination, metabolite removal, peak alignment and multivariate statistical analysis.
Collaborating with leaders in metabolite profiling, Waters enhanced the core capabilities of the application manager, allowing researchers to more easily process their data, visualise statistical results, interact with raw data, and dynamically search and store metabolic information in a relational database.
MarkerLynx DB is an essential component of Waters's total system solution for metabonomics.
Along with the company's Acquity LC system, high-resolution exact mass Premier family of mass spectrometers, and MassLynx 4.1 software, scientists have a cohesive solution for every metabonomics application, says the company.
• Waters: contact details and other news
• Email this article to a colleague
• Register for the free Laboratorytalk email newsletter
• Laboratorytalk Home Page
Search the Pro-Talk network of sites
