Technologies to enhance microplate assays

BMG LABTECH is attending the annual Miptec meeting in Basel, Switzerland from September 24th-27th 2012.

The company will showcase its newest technology at Booth A22.

As will be highlighted in several posters and at an Industry Symposium, BMG LABTECH will detail how its microplate reader technologies can improve scientific research.

When designing its newest microplate readers, BMG LABTECH analysed the market to determine what features are missing in a microplate reader that will enhance life science applications.

The company claims that two such advancements that greatly improve assays are ultra-fast, full spectrum analysis for absorbance assays and Direct Optic Bottom Reading for cell-based assays.

In the Industry Symposium on Tuesday afternoon September 25th, in conjunction with Labcyte and CISBIO, BMG LABTECH will show how its Direct Optic Bottom Reading can create an automated cell-based HTS screening platform that compliments or rivals slower HCS platforms.

With Direct Optic Bottom Reading on the PHERAstar FS, the signal-to-blank ratio in fluorescent cell-based assays like GFP, mCherry, and mOrange is more than 300% higher than on fiber optic plate readers. 

In addition, BMG LABTECH will highlight in a poster a new label-free system that can determine protein-protein binding kinetics using ultra-fast, full spectrum analysis in a spectrometer-based microplate reader.

In collaboration with PharmaDiagnostics, a label-free system that uses theirSoPRanoTM label-free technology and a BMG LABTECH spectrometer-based microplate reader has been designed.

Without the need to purchase expensive and dedicated equipment, this label-freesystem can quickly analyse and determine the KD values, EC/IC50s, as well as the association (ka) and dissociation (kd) rates for a protein-protein interaction.