Blue light transilluminator improves DNA imaging
Cambridge-based Syngene has unveiled its UltraBright-LED transilluminator designed to safely image fluorescent gel labels
The UltraBright-LED uses two high intensity LED arrays which produce uniform, bright excitation at 470nm, and can illuminate dyes that excite at 420 to 480nm.
As a result, the system is suitable for visualising small amounts of Ethidium Bromide and non-toxic DNA stains including Syngene's new UltraSafe Blue dye, SYBR Safe and GelGreen, as well as protein stains such as SYPRO Ruby and Pro-Q Diamond.
Since the UltraBright-LED uses blue light, researchers imaging non-toxic stains can use the system directly on the bench.
The transilluminator has been designed to slide in and out of any Syngene G:BOX imaging system, making the UltraBright-LED ideal for visualising faint bands, allowing precise band cutting and production of high quality images for analysis and publication.
Laura Sullivan, Syngene's Divisional Manager said: "Blue light transilluminators are an alternative to UV when scientists work with non-toxic fluorescent dyes." Sullivan added that the advantage of using blue light is that it is a safe light source which can be used on the bench, as it is not as harmful as UV and does not photo-nick DNA samples.
Syngene has launched the PXi Touch range of high resolution, multi-application image analysis systems.
Cambridge University is using the G:BOX XR5 to understand which genes are involved in remyelination.
Syngene bills U:Genius3 as a complete budget gel imaging system
Syngene's range of G:box Chemi image analysers can be used for imaging with infra-red Li-cor IRDye dyes, making it easier to detect and quantify different types of proteins on multiplex Western blots.
Syngene's Blue Light Transilluminator light box is designed for safe viewing of fluorescently labelled DNA and proteins, and is suitable for visualising nanogram amounts of non-toxic DNA stains.