Paraytec will be demonstrating a tool for surface dissolution imaging - the ActiPix SDI300 - at the 2009 American Association for Pharmaceutical Scientists (AAPS) meeting in Los Angeles, CA.
The SDI300 is a UV area imaging detector that enables quantitative imaging of surface phenomena of a range of substances, including APIs, formulations, gels, liquids, stents and patches.
Initial results indicate that the SDI300 also offers insights for researchers investigating bioavailability and real-time monitoring of dental erosion.
Compact in design, the SDI300 system includes ActiPix UV area imaging detection, dissolution imaging sample holder, integrated syringe pump and software that enables real-time quantitative recording and review of data.
The SDI300 uses a highly sensitive UV area imaging sensor to record, interrogate and analyse a variety of complex processes.
Operating wavelength (190-1100nm) can be selected to allow sensitive and selective monitoring of the substance of interest.
It offers accurate, quantitative and mechanistic information for a variety of applications.
Used as a tool for accelerated pre-formulations development, the SDI300 enables intrinsic dissolution rates to be obtained in less than 20min.
The ActiPix SDI300 provides insights into processes taking place from microns to millimetres under the surface, enabling erosion and dissolution phenomena to be visualised simultaneously.
